Identify a Specific Immune Profile in Patients With Chronic Pelvic Pain Resistant to First-line Treatments by Measuring Th1, Th2, Th17, and Treg Cytokines Produced After Non-specific Functional Cell Stimulation - ImmunoCPP

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-40
SponsorCentre Hospitalier Universitaire de Nice

About this trial

Chronic pelvic pain (CPP) affects more than one in four women. An immune imbalance in the Th1/Th2 balance has been reported in multiple CPP situations, particularly in patients with endometriosis, but with mixed results. The use of a functional immune test, already validated in previous indications and particularly in infertility, could simulate an immune stimulation similar to that of painful attacks.

Eligibility criteria

Qualifiers

Aged between 18 and 40;

Under continuous hormone treatment for at least 6 months;

Imaging less than 12 months old: either normal or showing endometriosis and/or adenomyosis lesions, excluding any other abnormalities that could explain the PCOS;

Affiliation with the French Social Security system;

Disqualifiers

Pregnant or breastfeeding women;

Autoimmune disease;

History of cancer within the last 5 years or currently undergoing treatment;

Current infectious syndrome;

Trial design

Treatments tested in this trial

  • Immune profile

Treatment groups

120 Participants
are divided into 2 treatment groups