Health TrialsbyHealthPanel

Impact 360 for Healthy Agers

ConditionHealthy Aging
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-75
SponsorUniversity of British Columbia

About this trial

The Impact 360 study will evaluate the effects of a combined intervention of exercise, mindfulness, and nutrition on 8 key indicators of health and the mechanisms that drive these changes. 60 subjects aged 50 to 75 without a current diagnosis of a brain disorder will be recruited. This study will follow a partial crossover design. All participants will receive the intervention. Participants randomized into the intervention group after their baseline screening will receive the 6-month intervention. Those randomized into the waitlist group will complete another assessment at the end of the 6-month care as usual phase before receiving the intervention.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Participants who are able to complete questionnaires and follow directions for interventions

Have access to a smartphone that can support the Fitbit app

Disqualifiers

Any neurological disease/disorder diagnosis (Ex: Parkinson's Disease, Multiple Sclerosis, Traumatic Brain Injury, Brain lesion, Stroke, etc)

Any chronic medical condition which would affect ability to participate in exercise

Any contraindication for exercise based on the Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and medical clearance form

Participants who were told by a medical doctor that they need to be medically supervised for exercise

Trial design

Design model

Crossover

Treatments tested in this trial

  • Exercise

    Behavioral

    The intervention will involve online (via University of British Colombia (UBC) Zoom videoconferencing) 1-hour moderate to high intensity exercise classes 3 times a week for 6 months

  • Meditation

    Behavioral

    The intervention will involve 15 minute guided mediation following exercise classes as well as mindfulness classes. Mindfulness classes will consist of 1.5 hour Mindfulness Based Stress Reduction (MBSR) classes for the first 2 months, followed by 1 month of 1 hour bi-weekly discussions and practice, then MBSR 2.0 for months 4 and 5, and 1 hour bi-weekly discussions and practice for the remaining month of the intervention.

  • Diet

    Behavioral

    The intervention will involve biweekly 1-hour nutrition and cooking classes with a dietician.

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Exercise, Diet, MindfulnessExperimental treatment 3 interventions
Group B: Waitlist GroupNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Cognition - NIH Toolbox Cognitive Battery

Cognition will be measured using the National Institutes of Health (NIH) Toolbox Cognitive battery (NIHTB-CB). Testing is done pre- and post-intervention to compare scores.

Time frame
6 Months
2

Cognition- Montreal Cognitive Assessment

Cognition will be measured using the Montreal Cognitive Assessment (MoCA). Testing is done pre- and post-intervention to compare scores.

Time frame
6 Months
3

Cognition- Parkinson's Disease Cognitive Rating Scale

Cognition will be measured using the Parkinson's Disease Cognitive Rating Scale (PD-CRS). Testing is done pre- and post-intervention to compare scores.

Time frame
6 Months
4

Inflammation and Biomarkers in Serum- High Sensitivity C-Reactive Protein

Systemic inflammation will be assessed by measuring concentrations of high sensitivity C-reactive protein (hs-CRP). Samples will be taken pre- and post-intervention to assess changes.

Time frame
6 Months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of British Columbia

Lead sponsor

The Jack and Darlene Poole Foundation

Collaborator

Source ClinicalTrials.gov
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