[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583145":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":58,"collaborators":26,"id":61,"slug":26,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":26,"enrollmentInfo":69,"targetDuration":26,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Pittsburgh","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Home-based prehabilitation exercise and nutrition (PRE)","EXPERIMENTAL","Interventions will include:\n\n* Up to 8 weeks of 3-5 times per week resistance training and 3-5 times per week of aerobic training.\n* Ensure Complete nutrition supplement drinks: 2 per day starting on the same day the exercise begins, up until 5 days prior to surgery.",[13],"Behavioral: Exercise and Nutrition",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care (CONT)","ACTIVE_COMPARATOR","The CONT group will not receive any intervention during study participation and undergo usual medical treatment and surveillance during the duration of the study.",[19],"Behavioral: Usual Care Group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Exercise and Nutrition","The exercise and nutrition intervention will last up to 8 weeks and will include:\n\n* 3-5 times per week of resistance training and 3-5 times per week of aerobic training. The prescribed exercise will be personalized based on the participant's baseline functionality.\n* Ensure Complete nutrition supplement drinks: 2 per day starting on the same day the exercise begins, up until 5 days prior to surgery.",[9],null,{"type":22,"name":28,"description":17,"armGroupLabels":29,"otherNames":26},"Usual Care Group",[15],[31],{"name":32,"affiliation":5,"role":33},"Melanie Potiaumpai, PhD, MPH","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":39},"Cara Battistella, MA","CONTACT","412-353-9102","battistellac@upmc.edu",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"UPMC Hillman Cancer Center","RECRUITING","Pittsburgh","Pennsylvania","15213","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-79.99589,40.44062,{"lat":53,"lon":52},[56],{"name":57,"role":37,"phone":38,"phoneExt":26,"email":39},"Cara Battistella",{"type":33,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Melanie Potiaumpai","Assistant Professor","100583145",false,"NCT06872515","Impact of Prehabilitation in Oncology Via Exercise- Esophageal (IMPROVE-Esophageal)","Impact of Prehabilitation in Oncology Via Exercise- Esophageal","Inclusion Criteria:\n\n* Men and women, age ≥ 18 years old\n* Diagnosed with esophageal cancer\n* Identified as esophagectomy surgery candidates at Hillman Cancer Center, UPMC Shadyside, or UPMC Passavant\n* ≥ 2 weeks until scheduled esophagectomy\n* ECOG Performance Status Scale score of ≤ 2\n* Ability to provide written informed consent\n* Ability to understand, speak, and read English.\n\nExclusion Criteria:\n\n* Evidence in the medical record of an absolute contraindication for exercise (e.g., Heart insufficiency \\> NYHA III or uncertain arrhythmia; uncontrolled hypertension; reduced standing or walking ability)\n* Any other comorbidities or musculoskeletal complications that preclude participation in the exercise programs as deemed by the exercise interventionist\n* Receiving non-esophagectomy related chemotherapy and\u002For radiotherapy\n* Active infections, hemorrhages, and cytopenias that could place surgical patients at risk for further adverse events, deemed by the exercise interventionist, physician, and\u002For nurse","ALL","18 Years",{"count":70,"type":71},20,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of this study is to determine the feasibility of a prehabilitation exercise and nutrition program (exercise and nutrition before a medical treatment) in adults with esophageal cancer before surgery (esophagectomy). The pre-surgery exercise and nutrition program will include resistance and aerobic training and nutrition supplementation during the weeks before surgery. We will also assess pre-surgical care needs in adults with esophageal cancer. Researchers will compare the exercise and nutrition intervention to usual care- which is standard medical care and post-surgery surveillance\u002Ffollow-up to understand the impact of exercise and nutrition before surgery. We will follow-up with participants before surgery, and after surgery at 2 weeks, 6 weeks, and 4-months at appointments that coincide with clinical follow-ups.\n\nThe main questions of this trials are:\n\n* Is exercise and nutrition supplementation before surgery for esophageal cancer feasible and acceptable to patients?\n* How does exercise and nutrition supplementation before surgery change physical function and psychosocial health?\n* What are important pre-surgical needs for adults with esophageal cancer?",[77,78],"Esophageal Cancer","Esophageal Carcinoma",[80,81,82,83,84],"Prehabilitation","Exercise","Esophageal cancer","Neoadjuvant chemotherapy","Pre-surgical exercise","2026-05-20",{"date":87,"type":88},"2026-05-26","ACTUAL",{"date":90,"type":88},"2025-07-16",{"date":92,"type":71},"2027-10-01",{"name":5,"class":6},1]