[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612465":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":37,"centralContacts":38,"locations":37,"responsibleParty":44,"collaborators":37,"id":46,"slug":37,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":37,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":37,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":69,"whyStopped":37,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":37},{"fullName":5,"class":6},"MarcoMateoRiera","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Psychotherapy","ACTIVE_COMPARATOR","Conventional psychotherapy for the treatment of depression.",[13],"Behavioral: Psychotherapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Exercise, therapeutic education and psychotherapy","EXPERIMENTAL","Graded activity in combination with exercise, therapeutic education and psychotherapy",[13,19],"Behavioral: Graded activity combined with exercise and education",[21,29],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Conventional psychotherapy for depression, including Acceptance and Commitment Therapy, Behavioral Activation, Cognitive Behavioral Therapy, Interpersonal Therapy, and Mindfulness-Based Cognitive Therapy.",[15,9],[26,27,28],"Acceptance and Commitment Therapy","Behavioral Activation","Cognitive Behavioral Therapy",{"type":22,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"Graded activity combined with exercise and education","This intervention consists of a graded activity program combined with exercise and therapeutic education in motor behavior to improve physical activity levels, self-efficacy and mood",[15],[34,35,36],"Biobehavioral physiotherapy","Therapeutic education","Exercise Therapy",null,[39],{"name":40,"role":41,"phone":42,"phoneExt":37,"email":43},"Roy La Touche, PhD","CONTACT","+34 917401980","roylatouche@lasallecampus.es",{"type":45,"investigatorFullName":37,"investigatorTitle":37,"investigatorAffiliation":37,"oldNameTitle":37,"oldOrganization":37},"SPONSOR","100612465",false,"NCT07253935","Impact of Therapeutic Exercise Integrated With Psychotherapy and Education in Patients With Depression","Efficacy of a Combined Approach of Therapeutic Exercise, Psychotherapy, and Therapeutic Education in Patients With Depression: The ACTIDEP Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of depression or dysthymia according to the ICD-11 criteria (including unspecified depressive disorder, code 6A7Z) or DSM-5-TR criteria confirmed by their referring physician.\n* A patient currently undergoing psychological treatment for depression with a score above the established cutoff in a validated depression questionnaire.\n\nExclusion Criteria:\n\n* Pregnancy.\n* Presence of neurological comorbidities or neurological signs.\n* Systemic rheumatic diseases, including fibromyalgia.\n* Central nervous system disorders.\n* Severe cognitive impairment.\n* Schizophrenia, psychotic disorders, or bipolar spectrum disorders.","ALL","18 Years","65 Years",{"count":56,"type":57},112,"ESTIMATED","INTERVENTIONAL",[60],"NA","The goal of this clinical trial is to evaluate whether a combined approach including therapeutic exercise, psychotherapy, and therapeutic education can improve depressive symptoms and quality of life in adults diagnosed with depression.\n\nThe main questions it aims to answer are:\n\nDoes a biobehavioral intervention that integrates exercise, psychotherapy, and education reduce depressive symptoms more effectively than psychotherapy alone? Does this combined approach improve quality of life, physical function, and sleep quality compared with standard psychological therapy? Researchers will compare the intervention group (therapeutic exercise + psychotherapy + education) to the control group (psychotherapy alone) to determine whether the integrated program provides greater improvements in mental health and well-being.\n\nParticipants will:\n\nComplete an initial assessment including demographic data, physical tests, and validated questionnaires.\n\nBe randomly assigned to one of the two groups. If in the intervention group, take part in an 8-week telematic program consisting of graded activity, therapeutic exercise, and educational sessions.\n\nUndergo post-intervention assessments and a follow-up evaluation 12 weeks after the program ends.\n\nThis study aims to provide evidence on whether combining therapeutic exercise and education with psychotherapy can enhance treatment outcomes and promote long-term adherence to physical activity in people with depression.",[63],"Depression Disorder",[65,66,67,68],"Mental disorders","Depression","Exercise","Physical activity","NOT_YET_RECRUITING","2025-11-26",{"date":72,"type":73},"2025-11-28","ACTUAL",{"date":75,"type":57},"2025-12-01",{"date":77,"type":57},"2027-05",{"name":5,"class":6}]