About this trial
The purpose of this study is to learn whether stimulation applied to the spinal cord through the skin (called transcutaneous spinal stimulation) can help control blood pressure in people with a spinal cord injury.
The main questions this study attempts to solve:
1. What are the immediate effects of spinal cord transcutaneous stimulation on BP? 2. Does stimulation produce lasting improvements in BP regulation and subsequently, daily function?
Eligibility criteria
Qualifiers
Individuals with a SCI ≥ 1 year after injury
Injury level ≥ T6 (thoracic level)
AIS grade A-C
Persistent hypotension (SBP < 90mmHg)
Disqualifiers
Current illness (e.g., infection, a pressure injury that might interfere with the intervention)
Ventilator-dependent
History of implanted brain/spine/nerve stimulators
Cardiac pacemaker/defibrillator or intra-cardiac lines
Trial design
Treatments tested in this trial
- Tilt test with stimulation (real-time effects): Intervention 1
- 20 sessions of stimulation (Intervention 2)
Treatment groups
Sponsors and collaborators
Kessler Foundation
Lead sponsor
Montclair State University
Collaborator