Impact of Vitamin C Supplementation on Hospital Outcomes in Children Undergoing Corrective Heart Surgery for Congenital Heart Diseases

ConditionCongenital Heart Disease (CHD)

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

AgeUp to 7

SponsorCairo University

About this trial

Vitamin C will be given before admission in the immediate preoperative preceding 7 days (the dose 30 -45 mg per day ) in oral drops preparations

Inflammatory markers including CRP , TLC ,PNI , GPS NLR will be checked on admission and on discharge and compared between cases and controls Hospital length stay will also be compared between the two groups

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Children in the first two years who will be for corrective surgery for heart diseases congenital heart diseases

Pediatric patients whose parents or caregivers agree to be enrolled in the study.

Risk Adjustment for Congenital Heart Surgery -1 (RACHS-1) for Evaluation of Mortality in Children Undergoing Cardiac Surgery : the first two categories (Thiagarajan and C. Laussen 2015)

Disqualifiers

Pediatric patients with associated comorbid conditions.

Trial design

Design model

Parallel

Treatments tested in this trial

Vitamin C
Other intervention
Vitamin C will be given before admission in the immediate preoperative preceding 7 days (the dose 30 -45 mg per day ) in oral drops preparations Inflammatory markers including CRP , TLC ,PNI , GPS NLR will be checked on admission and on discharge and compared between cases and controls Hospital length stay will also be compared between the two groups
Placebo
Other intervention
Placebo will be given before admission in the immediate preoperative preceding 7 days (the dose 30 -45 mg per day ) in oral drops preparations Inflammatory markers including CRP , TLC ,PNI , GPS NLR will be checked on admission and on discharge and compared between cases and controls

Treatment groups

20 Participants

are divided into 2 treatment groups

Group A: InterventionalExperimental treatment 1 intervention

Group B: The control groupPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

The improvemnents of Ejection Fraction between the two groups

Each group wil be evaluated for the eiection fraction before and after the operation and the improvement will be compared

Time frame

7-10 days

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cairo University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: