Implementing Depression and Adherence Treatment
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Miami
About this trial
The goal of this clinical trial is to compare a core set and enhanced set of implementation strategies in increasing the reach of evidence-based treatments to patients with HIV and depression. The main questions it aims to answer are:
What proportion of patients start an evidence-based treatment for depression (reach)? What percentage of patients show clinical improvement in depression and what percentage attain viral undetectability within one year (effectiveness)?
Researchers will compare high and low reach clinics to further inform tailored implementation strategies for uptake and maintenance.
Clinics will be randomized into one of two study arms: core versus enhanced strategies. In both arms, core strategies will be utilized. Enhanced clinics will also receive more resource-intensive training.
Eligibility criteria
Qualifiers
Clinics are eligible if they provide HIV primary care via the City of Cape Town (CoCT) Department of Health
Clinics will be assigned to the study upon notice of funding and before start up.
Are 18 years of age or older and
Have a detectable HIV viral load (operationalized as the lower limit of detection on the standard test is used at the local clinic), or presumed detectable viral load per clinic standards
Disqualifiers
None
Trial design
Treatments tested in this trial
- Core Implementation Strategies
- Enhanced Implementation Strategies
Treatment groups
10 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Miami
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator
Massachusetts General Hospital
Collaborator
University of Cape Town
Collaborator
Source ClinicalTrials.gov