About this trial
The purpose of this research is to determine whether a 16-week high intensity interval training (HIIT) exercise program will improve brain health among women undergoing chemotherapy and also improve cardiovascular (heart) function.
The names of the study interventions involved in this study are/is:
* High-Intensity Interval Training (HIIT)
Eligibility criteria
Qualifiers
Written informed consent prior to any study-related procedures
Women newly diagnosed (Stage I-III) breast cancer.
Over the age of 18 years; children under the age of 18 will be excluded due to rarity of disease
The effects of exercise on the developing fetus are unknown. For this reason, women of child-bearing potential must agree to undergo a pregnancy test and to use adequate contraception (hormonal or barrier method of birth control or abstinence) prior to study entry and for six months following duration of study participation. Should a woman become pregnant or suspect that she is pregnant while participating on the trial, she should inform her treating physician immediately.
Disqualifiers
Patients should not have any uncontrolled illness including ongoing or active infection, uncontrolled diabetes, hypertension or thyroid disease
Patients with other active malignancies are ineligible for this study.
Patients with metastatic disease
Medical history of coronary heart or artery disease, chronic or acute congestive heart failure or history of systolic or diastolic insufficiencies
Trial design
Treatments tested in this trial
- High-Intensity Intervals Training
- Attention Control
Treatment groups
Sponsors and collaborators
Dana-Farber Cancer Institute
Lead sponsor
American Institute for Cancer Research
Collaborator