[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536194":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":30,"responsibleParty":58,"collaborators":19,"id":61,"slug":19,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":19,"maxAge":19,"enrollmentInfo":68,"targetDuration":19,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":80,"overallStatus":33,"whyStopped":19,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"IRCCS Azienda Ospedaliero-Universitaria di Bologna","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Study group","EXPERIMENTAL","Cryopreserved Ovarian Tissue Reimplantation Using Platelet-enriched Autologous Plasma",[13],"Procedure: Cryopreserved Ovarian Tissue Reimplantation",[15],{"type":16,"name":17,"description":11,"armGroupLabels":18,"otherNames":19},"PROCEDURE","Cryopreserved Ovarian Tissue Reimplantation",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Diego Raimondo, MD","IRCCS AOU Bologna","STUDY_CHAIR",[26],{"name":22,"role":27,"phone":28,"phoneExt":19,"email":29},"CONTACT","0512143732","die.raimondo@gmail.com",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Diego Raimondo","RECRUITING","Bologna","BO","40138","Italy","IT",{"type":40,"coordinates":41},"Point",[42,43],11.33875,44.49381,{"lat":43,"lon":42},[46,49,52,54,56],{"name":22,"role":27,"phone":47,"phoneExt":48,"email":29},"0512144389","0039",{"name":50,"role":51,"phone":19,"phoneExt":19,"email":19},"Renato Seracchioli, MD","PRINCIPAL_INVESTIGATOR",{"name":22,"role":53,"phone":19,"phoneExt":19,"email":19},"SUB_INVESTIGATOR",{"name":55,"role":53,"phone":19,"phoneExt":19,"email":19},"Rossella Vicenti, PhD",{"name":57,"role":53,"phone":19,"phoneExt":19,"email":19},"Valentina Magnani, PhD",{"type":51,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Renato Seracchioli","Professor","100536194",false,"NCT06261658","Improving the Quality of Cryopreserved Ovarian Tissue Reimplantation Using Platelet-enriched Autologous Plasma","TESOVA2022","Inclusion Criteria:\n\n* request for cryopreserved ovarian tissue transplantation;\n* premature ovarian failure or irregular mentrual cycles;\n* negative test for HIV, HBV, HCV, Treponema pallidum;\n* negative PAP test;\n* oncological authorization;\n* absence of neoplastic contamination in the cryopreserved ovarian tissue;\n* Informed consent\n\nExclusion Criteria:\n\n* neoplastic contamination in cryopreserved ovarian tissue;\n* history of endometriosis;\n* endocrinological disorders present and not treated (uncompensated thyroid dysfunction, diabetes (type 1, type 2);\n* body mass index (BMI) \\>30 kg\u002Fm2;\n* circulating platelet level \\\u003C 150,000 \u002F mml;\n* bacterial infection;\n* ongoing use of anticoagulants;\n* bleeding diathesis.","FEMALE",{"count":69,"type":70},45,"ESTIMATED","INTERVENTIONAL",[73],"NA","The study is aimed to evaluate the effects of intraovarian injection of autologous Platelet-enriched Autologous Plasma on the outcomes of orthotopic transplantation of cryopreserved ovarian tissue.",[76,77,78,79],"Cryopreservation","Ovary Injury","Infertility, Female","Menopause Ovarian Failure",[81,82,83,84,85],"Cryopreserved Ovarian Tissue","Ovarian tissue transplantation","Platelet-enriched Autologous Plasma","ovarian endocrine function","livebirths","2024-02-08",{"date":88,"type":89},"2024-02-15","ACTUAL",{"date":91,"type":70},"2024-03-01",{"date":93,"type":70},"2033-12-29",{"name":5,"class":6},1]