Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorZeliha Alicikus
About this trial
The aim of this retrospective cohort study is to compare the safety and efficacy of induction agents for tracheal intubation in critically ill adult patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥ 18 years
Admission to the surgical ICU for critical care
Administration of one of the studied induction agents
Availability of complete clinical data
Disqualifiers
Age < 18 years
Absence of documented induction agent administration
Incomplete or missing medical records
Trial population
ICU admitted, critically ill patients The study population will include critically ill trauma patients aged 18 years and older who were admitted to the surgical intensive care unit
Trial design
Design model
Cohort
Time perspective
Retrospective
Treatments tested in this trial
induction type for intubation in ICU
Procedure/SurgeryClinical data documented throughout the course of hospitalization will be retrieved and analyzed.
Treatment groups
4 Participants
are divided into 4 treatment groupsGroup A: propofol1 intervention
Group B: ketamine1 intervention
Group C: ethomidate1 intervention
Group D: midazolam1 intervention
Trial outcomes
Primary outcomes
1
Primary Outcome will be all-cause mortality at day 7 following tracheal intubation
mortality at day 7
Time frame
day 7Secondary outcomes
1
Peri-intubation cardiovascular collapse
occurrence after induction
Time frame
perioperatively2
Clinical course outcomes
hospital mortality
Time frame
daysSponsors and contacts
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Zeliha Alicikus
Lead sponsor
Umraniye Education and Research Hospital
Sponsor institution
University of Florida
Collaborator
Source ClinicalTrials.gov