[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621726":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":13,"locations":10,"responsibleParty":23,"collaborators":10,"id":27,"slug":10,"hasResults":28,"nctId":29,"briefTitle":30,"officialTitle":31,"acronym":10,"eligibilityCriteria":32,"healthyVolunteers":33,"sex":34,"minAge":35,"maxAge":36,"enrollmentInfo":37,"targetDuration":10,"studyType":40,"phases":10,"briefSummary":41,"conditions":42,"keywords":10,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,11],{"label":9,"type":10,"description":10,"interventionNames":10},"rheumatoid arthritis patient",null,{"label":12,"type":10,"description":10,"interventionNames":10},"age and sex matched healthy control",[14,19],{"name":15,"role":16,"phone":17,"phoneExt":10,"email":18},"Amera I Abd el-Ghany, ass. lecturer","CONTACT","01003139319","amera_i95@yahoo.com",{"name":20,"role":16,"phone":21,"phoneExt":10,"email":22},"Eman M Shawky, lecturer","01063489998","eman202@aun.edu.eg",{"type":24,"investigatorFullName":25,"investigatorTitle":26,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Amera Imam Abdel - Ghany Ahmed","Assistant lecturer","100621726",false,"NCT07374367","Isthmin-1 as a Biomarker of Disease Activity in Rheumatoid Arthritis: Correlation With Musculoskeletal Ultrasound Findings","Serum Isthmin-1 Level as a Biomarker of Disease Activity in Rheumatoid Arthritis: Correlation With Musculoskeletal Ultrasound Findings","Inclusion Criteria:\n\n-Adult patients (≥18 years old) clinically diagnosed with rheumatoid arthritis according to the 2010 ACR\u002FEULAR classification criteria.\n\nExclusion Criteria:\n\n* Patients less than 18 years old.\n* Patients with other autoimmune diseases.\n* Participants with active infections, malignancies or diabetes.\n* Recent hand surgery, trauma, deformity and neurological conditions affecting hand function",true,"ALL","18 Years","65 Years",{"count":38,"type":39},66,"ESTIMATED","OBSERVATIONAL","The goal of this case control study is to detect serum isthmin-1 level in RA patient compered to healthy control . The main questions it aims to answer are:\n\nwhat is the serum isthmin-1 level in RA patient? what is the correlation between serum isthmin-1 and RA disease activity? what is the correlation between serum isthmin-1 level and MSUS finding in RA patients?",[43],"Disease Activity","NOT_YET_RECRUITING","2026-01-25",{"date":47,"type":48},"2026-01-28","ACTUAL",{"date":50,"type":39},"2026-05-01",{"date":52,"type":39},"2027-12-01",{"name":25,"class":6}]