Ketogenic Diet to Reduce Osteoarthritis Pain in MCI

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age55-75
SponsorUniversity of Kansas Medical Center

About this trial

Osteoarthritis and mild cognitive impairment are common conditions that share underlying biological processes related to metabolism and inflammation. This study will examine whether a well-formulated ketogenic diet influences pain, physical function, and cognitive outcomes in adults with osteoarthritis and mild cognitive impairment. Participants will follow a supervised ketogenic dietary intervention, with assessments conducted before and after the intervention to evaluate changes in symptoms and related biological markers. The goal of this study is to better understand shared mechanisms between joint pain and cognitive health and to explore whether a ketogenic dietary approach may support symptom management in these populations.

Eligibility criteria

Qualifiers

English speaking

Diagnosis of major joint osteoarthritis

Diagnosis of mild cognitive impairment

Disqualifiers

Diabetes that requires insulin

Cancer requiring chemo- or radiation therapy in the last 2 years

Cardiac event within 1 year

Recent history of renal stones

Trial design

Treatments tested in this trial

  • Well-formulated ketogenic diet

Treatment groups

10 Participants
are divided into 1 treatment group