[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100504564":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":19,"responsibleParty":35,"collaborators":37,"id":41,"slug":19,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":19,"enrollmentInfo":49,"targetDuration":19,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":19,"overallStatus":58,"whyStopped":19,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":19},{"fullName":5,"class":6},"Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Hight Myopa","EXPERIMENTAL","Large Cohort of patients with hight Myopa",[13],"Other: Structural and fonctional phynotyping",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Structural and fonctional phynotyping","The additioan acts in this research are:\n\nFonctionnal phenotyping:Retinal sensitivity and fixation stability assessment using microperimetry, assessment of long-term fixation stability Structural Phenotyping: Anterior segment examination with OCT anterior Blood sample collection",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Ramin TADAYONI, Pr","Hôpital Fondation Adolphe de Rothschild","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},"Nabil BROUK","CONTACT","+331 40 02 11 26","nbrouk@15-20.fr",{"name":32,"role":28,"phone":33,"phoneExt":19,"email":34},"Hayet SERHANE","+331 40 02 11 44","hserhane@15-20.fr",{"type":36,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR",[38],{"name":39,"class":40},"Fondation Ophtalmologique Adolphe de Rothschild","NETWORK","100504564",false,"NCT05849974","Large Cohort of 1000 Patients With Severe Myopia","MyoCo1000","Inclusion Criteria:\n\n* Age ≥ 6 years\n* Severe myopia in at least one eye, defined as\n\n  * a refractive error ≤ -6.00 diopters OR\n  * an axial length ≥ 26.50 mm\n* Follow-up performed at at least one of the participating centers\n* Express consent to participate in the study\n* If age \\\u003C 18 years: express consent of the person(s) exercising parental authority\n* Affiliated or beneficiary of a health insurance\n\nExclusion Criteria:\n\n* Visual acuity \\\u003C 5 letters on the ETDRS (equivalent to \"finger count\" or less) in both eyes\n* Disorders of the transparent media in both eyes with opacities that may affect image quality\n* Syndromic myopia of genetic origin (Stickler syndrome type 1 and 2, Marfan syndrome, Ehler-Danlos disease type 4, Knobloch syndrome) or inherited retinal dystrophy (X-linked retinitis pigmentosa, congenital stationary night blindness of Schubert-Bornshein type, Bornholm eye disease)\n* Patient who does not wish to continue to be followed in one of the participating centers\n* Patient benefiting from a legal protection measure\n* Pregnant or breastfeeding woman","ALL","6 Years",{"count":50,"type":51},1000,"ESTIMATED","INTERVENTIONAL",[54],"NA","The prevalence of myopia and severe myopia are increasing and will affect 50% and 10% of the population respectively. Severe myopia exposes an increased risk of glaucoma, cataract, retinal detachment and myopic maculopathy, a source of visual impairment.\n\nTo date, no European cohort study has been conducted to estimate the rate of these complications and to study the predictive parameters.",[57],"Myopia, Severe","NOT_YET_RECRUITING","2023-05-22",{"date":61,"type":62},"2023-05-23","ACTUAL",{"date":64,"type":51},"2023-06",{"date":66,"type":51},"2038-05",{"name":5,"class":6}]