[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634332":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":54,"collaborators":56,"id":62,"slug":26,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":26,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":92,"whyStopped":26,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Taipei City Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Laser Acupuncture Group","EXPERIMENTAL","Active low-level laser therapy at 7 specific acupoints.",[13],"Device: Low-Level Laser Acupuncture (LA)",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Control Group","SHAM_COMPARATOR","Inactive laser treatment using an identical-looking device without energy output.",[19],"Device: Sham Laser Acupuncture",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Low-Level Laser Acupuncture (LA)","Device: Low-level laser therapy (LLLT) device. Acupoints: KI1 (Yongquan), ST36 (Zusanli), SP10 (Xuehai), PC8 (Laogong), EX-UE9 (Bafeng), EX-UE9 (Baxie), and LU9 (Taiyuan).\n\nDosage\u002FFrequency: Administered 3 times per week during the hemodialysis process for 4 weeks.\n\nDuration: Each treatment session lasts approximately 15 to 30 minutes.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham Laser Acupuncture","Description:Device: An inactive sham laser device that is identical in appearance and operational procedure to the active device.\n\nProcedure: The device will be applied to the same 7 acupoints (KI1, ST36, SP10, PC8, Bafeng, Baxie, LU9) for 15-30 minutes.\n\nBlinding: The device will not emit actual laser energy but will mimic the treatment process to maintain participant blinding.\n\nFrequency: 3 times per week for 4 weeks during hemodialysis.",[15],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Ming Jen Wang, MD","CONTACT","+886-930-766-631","wanters0800@gmail.com",{"name":38,"role":34,"phone":39,"phoneExt":26,"email":40},"Chao-Tsung Chen, Ph.D.","+886-979-306-080","dai44@tpech.gov.tw",[42],{"facility":43,"status":26,"city":44,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":26,"geoPoint":26,"contacts":48},"Taipei City Hospital, Renai Branch","Taipei","106","Taiwan","TW",[49,50],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"name":33,"role":34,"phone":51,"phoneExt":52,"email":53},"886-02-2709-3600","5213","dba77@tpech.gov.tw",{"type":55,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[57,60],{"name":58,"class":59},"National Yang Ming Chiao Tung University","OTHER",{"name":61,"class":59},"National Taiwan University of Science and Technology","100634332",false,"NCT07538310","Laser Acupuncture for Fatigue in Hemodialysis Patients","Laser Acupuncture Improves Fatigue and Quality of Life in Hemodialysis Patients: a Randomized Double-blind Clinical Trial Pilot Study","LA-HD-Fatigue","Inclusion Criteria:\n\n* Patients with End-Stage Renal Disease (ESRD) who require regular maintenance hemodialysis.\n* Must undergo hemodialysis treatment at least 3 times per week.\n* Aged 18 years or older.\n* Willing and able to provide informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Presence of acute infectious symptoms.\n* Unstable vital signs.\n* Diagnosis of malignant tumors.\n* Pregnancy.\n* Presence of open wounds at the sites designated for laser intervention.\n* Patients with implanted cardiac pacemakers or other cardiac devices.","ALL","18 Years",{"count":72,"type":73},50,"ESTIMATED","INTERVENTIONAL",[76],"NA","The goal of this clinical trial is to learn if laser acupuncture (low-level laser therapy) works to treat fatigue and improve quality of life in adults with end-stage renal disease (ESRD) undergoing hemodialysis. It will also learn about how laser acupuncture affects blood circulation and autonomic nervous system balance.\n\nThe main questions it aims to answer are:\n\n1. Does laser acupuncture reduce the severity of fatigue and its interference with daily life?\n2. Can laser acupuncture improve related symptoms such as insomnia, poor appetite, and skin itching?\n3. How does laser acupuncture affect objective markers like microcirculation and heart rate variability? Researchers will compare laser acupuncture to a sham treatment (a look-alike procedure using a device that does not emit a laser) to see if laser acupuncture works to treat fatigue.\n\nParticipants will:\n\n1. Receive laser acupuncture or a sham treatment during their regular hemodialysis sessions 3 times a week for 4 weeks.\n2. Have their fatigue and life quality assessed through questionnaires on the first day, at 4 weeks, and at 8 weeks.\n3. Undergo non-invasive tests to measure microcirculation, heart rate variability, and pulse waves, and have photos of their tongue taken for Chinese medicine assessment.",[79,80,81],"ESRD (End Stage Renal Disease)","Dialysis","Fatigue",[83,84,85,86,81,87,88,89,90,91],"Hemodialysis","End-Stage Renal Disease","Laser Acupuncture","Photobiomodulation","Quality of Life","Microcirculation","Low-Level Laser Therapy","Traditional Chinese Medicine","Heart Rate Variability","NOT_YET_RECRUITING","2026-04-12",{"date":95,"type":96},"2026-04-20","ACTUAL",{"date":98,"type":73},"2026-04-08",{"date":100,"type":73},"2027-08-31",{"name":5,"class":6},1]