LATe Cerclage in High-risk Pregnancies (LATCH)
ConditionPremature Birth
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-50
SponsorThomas Jefferson University
About this trial
The goal of this clinical trial is to determine whether cervical cerclage reduces the risk of preterm birth in patients with a short transvaginal ultrasound (TVU) cervical length (CL) ≤25mm between 24 0/7-26 6/7 weeks.
Eligibility criteria
Qualifiers
18-50 years old, pregnant, assigned female at birth
Singleton pregnancy
TVU CL ≤25mm between 24 0/7 - 26 6/7 weeks of gestation
Disqualifiers
Initial multifetal gestation with subsequent multifetal pregnancy reduction, or selective fetal termination performed >14 weeks, or cotwin pregnancy loss diagnosed >14 weeks
Cerclage in situ
Preterm labor, defined as painful regular uterine contractions and change in cervical dilation
PPROM
Trial design
Treatments tested in this trial
- Cervical cerclage
- Vaginal Suppository Progesterone
Treatment groups
329 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov