[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617475":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":14,"centralContacts":18,"locations":26,"responsibleParty":181,"collaborators":183,"id":188,"slug":7,"hasResults":189,"nctId":190,"briefTitle":191,"officialTitle":192,"acronym":193,"eligibilityCriteria":194,"healthyVolunteers":189,"sex":195,"minAge":196,"maxAge":7,"enrollmentInfo":197,"targetDuration":200,"studyType":201,"phases":7,"briefSummary":202,"conditions":203,"keywords":207,"overallStatus":213,"whyStopped":7,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":223},{"fullName":5,"class":6},"University Hospital, Montpellier","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":12},"Venous blood sampling","Five 6-7 ml EDTA tubes of venous blood will be collected at two points during the care pathway:\n\n* Immediately before the endoscopic procedure, at the time of catheter insertion for general anesthesia. This is to study the signal intensity at a baseline stage.\n* Between 2 and 6 weeks after submucosal dissection (only in cases of pT1 adenocarcinoma) and before any further surgery for pT1 cancer. This is to study the presence or absence of a residual signal after local resection.",[13],"Blood sample",[15],{"name":16,"affiliation":5,"role":17},"Antoine DEBOURDEAU, MD","STUDY_CHAIR",[19,23],{"name":16,"role":20,"phone":21,"phoneExt":7,"email":22},"CONTACT","+334.67.33.07.83","a-debourdeau@chu-montpellier.fr",{"name":24,"role":20,"phone":7,"phoneExt":7,"email":25},"Catherine PANABIERES, MD, PhD","c-panabieres@chu-montpellier.fr",[27,43,56,69,82,95,108,118,129,142,155,168],{"facility":28,"status":7,"city":29,"state":7,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"University Hospital of Amiens","Amiens","80054","France","FR",{"type":34,"coordinates":35},"Point",[36,37],2.3,49.9,{"lat":37,"lon":36},[40],{"name":41,"role":20,"phone":7,"phoneExt":7,"email":42},"Clara YZET, MD","yzet.clara@chu-amiens.fr",{"facility":44,"status":7,"city":45,"state":7,"zip":46,"country":31,"countryCode":32,"cosmosGeoPoint":47,"geoPoint":51,"contacts":52},"University Hospital of Bordeaux","Bordeaux","33604",{"type":34,"coordinates":48},[49,50],-0.58046,44.84124,{"lat":50,"lon":49},[53],{"name":54,"role":20,"phone":7,"phoneExt":7,"email":55},"Arthur BERGER, MD","arthur.berger@chu-bordeaux.fr",{"facility":57,"status":7,"city":58,"state":7,"zip":59,"country":31,"countryCode":32,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"University Hospital of Brest","Brest","29200",{"type":34,"coordinates":61},[62,63],-4.48628,48.39029,{"lat":63,"lon":62},[66],{"name":67,"role":20,"phone":7,"phoneExt":7,"email":68},"Lucille QUENEHERVE, MD","lucille.queneherve@chu-brest.fr",{"facility":70,"status":7,"city":71,"state":7,"zip":72,"country":31,"countryCode":32,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"University Hospital of Dijon","Dijon","21079",{"type":34,"coordinates":74},[75,76],5.01391,47.31344,{"lat":76,"lon":75},[79],{"name":80,"role":20,"phone":7,"phoneExt":7,"email":81},"Thibault DEGAND, MD","thibault.degand@chu-dijon.fr",{"facility":83,"status":7,"city":84,"state":7,"zip":85,"country":31,"countryCode":32,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"University Hospital of Limoges","Limoges","87042",{"type":34,"coordinates":87},[88,89],1.24759,45.83362,{"lat":89,"lon":88},[92],{"name":93,"role":20,"phone":7,"phoneExt":7,"email":94},"Jeremy JACQUES, MD, PhD","jeremie.jacques@chu-limoges.fr",{"facility":96,"status":7,"city":97,"state":7,"zip":98,"country":31,"countryCode":32,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"Civil Hospices of Lyon","Lyon","69003",{"type":34,"coordinates":100},[101,102],4.84789,45.74906,{"lat":102,"lon":101},[105],{"name":106,"role":20,"phone":7,"phoneExt":7,"email":107},"Mathieu PIOCHE, MD, PhD","mathieu.pioche@chu-lyon.fr",{"facility":109,"status":7,"city":97,"state":7,"zip":110,"country":31,"countryCode":32,"cosmosGeoPoint":111,"geoPoint":113,"contacts":114},"Jean Mermoy Private Hospital","69008",{"type":34,"coordinates":112},[101,102],{"lat":102,"lon":101},[115],{"name":116,"role":20,"phone":7,"phoneExt":7,"email":117},"Sarah LEBLANC, MD","sarahleblanc34@hotmail.com",{"facility":119,"status":7,"city":120,"state":7,"zip":121,"country":31,"countryCode":32,"cosmosGeoPoint":122,"geoPoint":126,"contacts":127},"University Hospital of Montpellier","Montpellier","34095",{"type":34,"coordinates":123},[124,125],3.87635,43.61093,{"lat":125,"lon":124},[128],{"name":16,"role":20,"phone":7,"phoneExt":7,"email":22},{"facility":130,"status":7,"city":131,"state":7,"zip":132,"country":31,"countryCode":32,"cosmosGeoPoint":133,"geoPoint":137,"contacts":138},"University Hospital of Nancy","Nancy","54511",{"type":34,"coordinates":134},[135,136],6.18496,48.68439,{"lat":136,"lon":135},[139],{"name":140,"role":20,"phone":7,"phoneExt":7,"email":141},"SCHAEFFER Marion, MD","M.SCHAEFER@chru-nancy.fr",{"facility":143,"status":7,"city":144,"state":7,"zip":145,"country":31,"countryCode":32,"cosmosGeoPoint":146,"geoPoint":150,"contacts":151},"University Hospital of Nîmes","Nîmes","30029",{"type":34,"coordinates":147},[148,149],4.35788,43.83665,{"lat":149,"lon":148},[152],{"name":153,"role":20,"phone":7,"phoneExt":7,"email":154},"Ludovic CAILLO, MD","ludovic.caillo@chu-nimes.fr",{"facility":156,"status":7,"city":157,"state":7,"zip":158,"country":31,"countryCode":32,"cosmosGeoPoint":159,"geoPoint":163,"contacts":164},"Saint Joseph Hospital","Paris","75014",{"type":34,"coordinates":160},[161,162],2.3488,48.85341,{"lat":162,"lon":161},[165],{"name":166,"role":20,"phone":7,"phoneExt":7,"email":167},"Yann LE BALEUR, MD","ylebaleur@ghpsj.fr",{"facility":169,"status":7,"city":170,"state":7,"zip":171,"country":31,"countryCode":32,"cosmosGeoPoint":172,"geoPoint":176,"contacts":177},"University Hospital of Rennes","Rennes","35033",{"type":34,"coordinates":173},[174,175],-1.67431,48.11109,{"lat":175,"lon":174},[178],{"name":179,"role":20,"phone":7,"phoneExt":7,"email":180},"Timothée WALLENHORST, MD","Timothee.WALLENHORST@chu-rennes.fr",{"type":182,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[184,186],{"name":185,"class":6},"University Hospital, Limoges",{"name":187,"class":6},"Société Nationale Française de Gastroentérologie","100617475",false,"NCT07319104","Liquid Biopsy in Early Colorectal Lesions","Biobank for Validating Liquid Biopsy in Predicting the Prognosis of Superficial Colonic Lesions","FECCO-BioBank","Inclusion Criteria:\n\n* Patient of legal age (≥ 18 years)\n* Patient with a superficial colonic tumor refered for submucosal dissection\n* Patient included in the FECCo cohort (patients will be included concomitantly in FECCO-Biobank)\n* Patient wishing to participate in the FECCO-BioBank biological collection\n\nExclusion Criteria:\n\n* Person with significant comorbidities preventing blood sampling\n* Patients with a distant metastasis detected by imaging\n* Person unable to read and write French\n* Person who have expressed their opposition to participating in this research after being informed by an investigator and having read the information sheet\n* Person not benefiting from a national health insurance scheme\n* Person under legal protection, guardianship or curatorship\n* Person participating in other study with an ongoing exclusion period","ALL","18 Years",{"count":198,"type":199},1000,"ESTIMATED","3 Months","OBSERVATIONAL","Early colorectal cancer screening increasingly detects small superficial colonic lesions, but current diagnostic tools still struggle to distinguish benign from malignant lesions and to assess lymph node risk. As histology after resection has limited accuracy, many patients undergo unnecessary surgery.\n\nLiquid biopsy, analyzing circulating biomarkers such as tumor DNA, extracellular vesicles, and nucleosomes, offers a non-invasive way to better classify these lesions. Emerging evidence suggests it may outperform current criteria for predicting lymph node involvement in T1 colorectal cancer.\n\nThis study will establish a biobank of 1,000 patients to identify blood-based signatures that predict tumor stage and lymph node status. The hypothesis of the study is that circulating biomarkers can accurately differentiate benign from malignant lesions and identify patients with or without lymph node metastasis.",[204,205,206],"Colorectal Neoplasms","Precancerous Conditions","Adenocarcinoma of the Colon",[208,209,210,211,212],"Lymphatic Metastasis","Endoscopy, Gastrointestinal","Liquid Biopsy","Biomarkers","Biobanking","NOT_YET_RECRUITING","2026-05-29",{"date":216,"type":217},"2026-06-02","ACTUAL",{"date":219,"type":199},"2026-06-15",{"date":221,"type":199},"2031-12-15",{"name":5,"class":6},12]