[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628822":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":35,"centralContacts":40,"locations":46,"responsibleParty":60,"collaborators":64,"id":66,"slug":11,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":11,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":11,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":49,"whyStopped":11,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Low-level laser therapy group","EXPERIMENTAL",null,[13],"Procedure: Low Level Laser Therapy",{"label":15,"type":10,"description":11,"interventionNames":16},"Piezocision group",[17],"Procedure: Piezocision",{"label":19,"type":20,"description":11,"interventionNames":11},"Control group","NO_INTERVENTION",[22,29],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"PROCEDURE","Low Level Laser Therapy","On both right and left sides, LLLT will be performed at the beginning of canine retraction, after 3, 7, 14 days, and then every 14 days for a total four-month period.",[9],[28],"LLLT",{"type":23,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"Piezocision","On both right and left sides, a minimally invasive flapless piezocision procedure will be performed each month from the beginning of the canine retraction for a total four-month period.",[15],[34],"Piezosurgery",[36],{"name":37,"affiliation":38,"role":39},"Farouk A Hussein, Professor","Professor in Orthodontics; Faculty of Dental Medicine, Boys, Cairo; Al-Azhar University","STUDY_CHAIR",[41],{"name":42,"role":43,"phone":44,"phoneExt":11,"email":45},"Hesham N Al-Qamhawy","CONTACT","00201099767929","heshamnabil96@gmail.com",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":11,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":11},"Outpatient Clinics of the Department of Orthodontics, Faculty of Dental Medicine, Boys, Cairo, Al-Azhar University.","RECRUITING","Cairo","Cairo Governorate","Egypt","EG",{"type":55,"coordinates":56},"Point",[57,58],31.24967,30.06263,{"lat":58,"lon":57},{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Hesham Nabil Ali Al-Qamhawy","Principal Investigator",[65],{"name":5,"class":6},"100628822",false,"NCT07466641","LLLLT vs Piezocision in Accelerating Orthodontic Canine Retraction","Effectiveness of Piezocision Versus Low-level Laser Therapy During Orthodontic Canine Retraction: A Comparative Controlled Clinical Study","Inclusion Criteria:\n\n* Age range 18-25 years.\n* Patients with crowding or protrusion requiring at least bilateral maxillary first premolar extraction followed by symmetrical canine retraction.\n* Full set of permanent dentition (third molar not considered).\n* Patients with good oral hygiene.\n\nExclusion Criteria:\n\n* Previous orthodontic treatment.\n* Patients taking medications or suffering from systemic conditions that can affect orthodontic tooth movement.\n* Active periodontal diseases and\u002For untreated carious lesions.\n* Congenital orofacial deformities.\n\nDiscontinuation criteria:\n\n* Multiple missing appointments.\n* Poor oral hygiene.\n* Multiple broken appliances to the extent that interferes with obtaining the treatment objectives.","ALL","18 Years","25 Years",{"count":76,"type":77},21,"ESTIMATED","INTERVENTIONAL",[80],"NA","This comparative controlled clinical study aims to evaluate and compare the effectiveness of piezocision and low-level laser therapy (LLLT) as adjunctive interventions to accelerate orthodontic canine retraction. Participants will be randomly assigned to one of three groups: piezocision, LLLT, or a control group (no adjunctive procedure). The study will assess the impact of these interventions on the rate of tooth movement, the type of tooth movement, and patient experience.",[83,84,85],"Malocclusion, Angle Class II, Division 1","Bimaxillary Protrusion","Class I Malocclusion",[87,88,89,90,91,92],"canine retraction","Low-level laser therapy","laser","piezocision","piezosurgery","orthodontic canine retraction","2026-05-06",{"date":95,"type":96},"2026-05-11","ACTUAL",{"date":98,"type":96},"2026-04-01",{"date":100,"type":77},"2027-06",{"name":62,"class":6},1]