M-TAPA vs ESPB for Postoperative Analgesia After Laparoscopic Cholecystectomy

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorBaşakşehir Çam & Sakura City Hospital

About this trial

Postoperative pain after laparoscopic cholecystectomy can negatively affect patient comfort, recovery, and opioid consumption. Regional abdominal wall blocks are commonly used as part of multimodal analgesia to improve postoperative pain control and reduce opioid-related side effects.

The modified thoracoabdominal nerve block through the perichondrial approach (M-TAPA) and the erector spinae plane block (ESPB) are two ultrasound-guided regional anesthesia techniques that have been shown to provide effective postoperative analgesia in abdominal surgery. However, comparative clinical data between these two techniques in laparoscopic cholecystectomy are limited.

This randomized, single-blind clinical trial aims to compare the postoperative analgesic effectiveness of M-TAPA and ESPB in adult patients undergoing elective laparoscopic cholecystectomy. Postoperative pain scores, opioid consumption, time to first analgesic requirement, and patient satisfaction will be evaluated.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult patients aged 18-65 years

ASA physical status I-III

Scheduled for elective surgery under general anesthesia

Ability to understand the study procedures and provide written informed consent

Disqualifiers

Refusal to participate

Known allergy to local anesthetics

Coagulation disorders or anticoagulant therapy

Infection at the injection site

Trial design

Design model

Parallel

Treatments tested in this trial

  • Modifiye throcoabdominal nerve block through the perichondrial approach (M-TAPA)

    Procedure/Surgery

    An ultrasound-guided modified thoracoabdominal nerve block through the perichondrial approach (M-TAPA) performed bilaterally using local anesthetic for postoperative analgesia after laparoscopic cholecystectomy.

  • erector spinae plane block (ESPB)

    Procedure/Surgery

    An ultrasound-guided erector spinae plane block (ESPB) performed using local anesthetic for postoperative analgesia after laparoscopic cholecystectomy.

Treatment groups

124 Participants
are divided into 2 treatment groups
Group A: M-TAPA BlockExperimental treatment 1 intervention
Group B: ESPBExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Total Opioid Consumption in the First 24 Hours

Total cumulative opioid consumption within the first 24 hours after surgery, recorded as intravenous tramadol equivalent dose.

Time frame
within the first 24 hours postoperatively

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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