About this trial
Postoperative pain after laparoscopic cholecystectomy can negatively affect patient comfort, recovery, and opioid consumption. Regional abdominal wall blocks are commonly used as part of multimodal analgesia to improve postoperative pain control and reduce opioid-related side effects.
The modified thoracoabdominal nerve block through the perichondrial approach (M-TAPA) and the erector spinae plane block (ESPB) are two ultrasound-guided regional anesthesia techniques that have been shown to provide effective postoperative analgesia in abdominal surgery. However, comparative clinical data between these two techniques in laparoscopic cholecystectomy are limited.
This randomized, single-blind clinical trial aims to compare the postoperative analgesic effectiveness of M-TAPA and ESPB in adult patients undergoing elective laparoscopic cholecystectomy. Postoperative pain scores, opioid consumption, time to first analgesic requirement, and patient satisfaction will be evaluated.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adult patients aged 18-65 years
ASA physical status I-III
Scheduled for elective surgery under general anesthesia
Ability to understand the study procedures and provide written informed consent
Disqualifiers
Refusal to participate
Known allergy to local anesthetics
Coagulation disorders or anticoagulant therapy
Infection at the injection site
Trial design
Parallel
Treatments tested in this trial
Modifiye throcoabdominal nerve block through the perichondrial approach (M-TAPA)
Procedure/SurgeryAn ultrasound-guided modified thoracoabdominal nerve block through the perichondrial approach (M-TAPA) performed bilaterally using local anesthetic for postoperative analgesia after laparoscopic cholecystectomy.
erector spinae plane block (ESPB)
Procedure/SurgeryAn ultrasound-guided erector spinae plane block (ESPB) performed using local anesthetic for postoperative analgesia after laparoscopic cholecystectomy.
Treatment groups
Trial outcomes
Primary outcomes
Total Opioid Consumption in the First 24 Hours
Total cumulative opioid consumption within the first 24 hours after surgery, recorded as intravenous tramadol equivalent dose.
Locations
Sponsors and contacts
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