[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643176":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":24,"responsibleParty":37,"collaborators":24,"id":41,"slug":24,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":24,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":24,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":24,"overallStatus":59,"whyStopped":24,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":24},{"fullName":5,"class":6},"Middle East University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Study group","ACTIVE_COMPARATOR","30 women with fibromyalgia who will receive manual diaphragmatic release sessions followed by a structured aerobic training program on a cycle ergometer for 8 weeks",[13,14],"Other: Manual Diaphragmatic Release","Other: Aerobic Training",{"label":16,"type":10,"description":17,"interventionNames":18},"Control group","30 women with fibromyalgia who will participate in the standardized aerobic training program alone for 8 weeks.",[14],[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Manual Diaphragmatic Release","Thrice a week for 8 weeks, the participant will assume a supine position with relaxed limbs. The therapist will position themselves at the head of the participant and make manual contact with the pisiform, hypothenar region, and the last three fingers on both sides, underneath the seventh to tenth rib costal cartilages. During the inspiratory phase, the therapist gently pulls the contact points toward the head and slightly laterally, progressively deepening contact within the costal margin over successive respiratory cycles to release restriction.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Aerobic Training","3 sessions per week consisting of 30-45 minutes of cycling at low-to-moderate intensity on a cycle ergometer. Intensity will be managed at a workout heart rate ranging between 60% to 70% of the maximal heart rate, accompanied by a brief warm-up and cool-down phase.",[16,9],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Saher Lotfy Elgayar, Ph.D","CONTACT","+201020429911","saherlotfy020@gmail.com",{"name":36,"role":32,"phone":24,"phoneExt":24,"email":24},"Mohammed Youssef Elhamrawy, Ph.D",{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Saher Lotfy El Gayar","Assistant Professor of Physical Therapy","100643176",false,"NCT07641166","Manual Diaphragmatic Release on Exercise Capacity and Quality of Life in Women With Fibromyalgia","Effect of Manual Diaphragmatic Release on Exercise Capacity and Quality of Life in Women With Fibromyalgia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Confirmed clinical diagnosis of fibromyalgia fulfilling the American College of Rheumatology diagnostic criteria.\n* Sedentary or low physical activity status (not participating in structured exercise programs within the past 3 months).\n\nExclusion Criteria:\n\n* Severe psychiatric comorbidities (e.g., major depressive disorder with active suicidal ideation) or cognitive impairments.\n* Presence of comorbid rheumatologic or autoimmune conditions that overlap with muscle\u002Fjoint symptoms (e.g., severe rheumatoid arthritis, systemic lupus erythematosus).\n* Primary chronic respiratory\u002Fchest diseases (e.g., severe COPD or active asthma).\n* Cardiovascular disorders or uncontrolled hypertension.\n* Pregnancy.","FEMALE","18 Years","55 Years",{"count":51,"type":52},60,"ESTIMATED","INTERVENTIONAL",[55],"NA","Evaluate the effect of manual diaphragmatic release on exercise capacity, inspiratory muscles strength, symptoms severity, and health-related quality of life in women diagnosed with fibromyalgia.",[58],"Fibromyalgia","NOT_YET_RECRUITING","2026-06-08",{"date":62,"type":63},"2026-06-11","ACTUAL",{"date":65,"type":52},"2026-06-17",{"date":67,"type":52},"2026-11-08",{"name":5,"class":6}]