[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100184314":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":44,"responsibleParty":60,"collaborators":62,"id":66,"slug":24,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":24,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":24,"enrollmentInfo":74,"targetDuration":24,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":24,"overallStatus":87,"whyStopped":24,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Centre hospitalier de l'Université de Montréal (CHUM)","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Repeated Measurements of Knee Alignment and Kinematics","ACTIVE_COMPARATOR","Patients in the Repeated Measurements Arm will have the kinematic measurement protocol repeated twice before and twice after the surgical procedure; the procedure itself will be performed with the traditional technique, i.e without guidance by the system.",[13],"Device: Repeated Measurements of Knee Alignment and Kinematics",{"label":15,"type":10,"description":16,"interventionNames":17},"Computer Guidance of Surgical Actions","Patients in the Computer Guidance of Surgical Actions Arm will have the kinematic measurement protocol performed only once before and once after the surgical procedure; the procedure itself will be performed with guidance by the system.",[18],"Device: Computer Guidance of Surgical Actions",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Repeated Measurements of Knee Alignment and Kinematics using tools developed by Eiffel Medtech Inc.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Computer Guidance of Surgical Actions using tools developed by Eiffel Medtech Inc.",[15],[29],{"name":30,"affiliation":31,"role":32},"Frédéric Lavoie, MD, MSc, FRCSC","CHUM","PRINCIPAL_INVESTIGATOR",[34,40],{"name":35,"role":36,"phone":37,"phoneExt":38,"email":39},"Frédéric Lavoie, MD MSc FRCSC","CONTACT","1-514-890-8000","25900","fredericlavoiemd@gmail.com",{"name":41,"role":36,"phone":37,"phoneExt":42,"email":43},"Fidaa Al-Shakfa, MSc","26103","f.alshakfa.crchum@gmail.com",[45],{"facility":46,"status":24,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Centre Hospitalier de l'Université de Montréal (CHUM)","Montreal","Quebec","H2L 4M1","Canada","CA",{"type":53,"coordinates":54},"Point",[55,56],-73.58781,45.50884,{"lat":56,"lon":55},[59],{"name":35,"role":32,"phone":24,"phoneExt":24,"email":24},{"type":61,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[63],{"name":64,"class":65},"Eiffel Medtech","INDUSTRY","100184314",false,"NCT01674816","Minimally Invasive Three-dimensional Knee Kinematic Assessment and Surgical Guidance Using Ultrasonic Rigid Registration","(Étude de la cinématique Tridimensionnelle du Genou et Guidage Chirurgical Minimalement Effractifs Par Recalage Rigide échographique)","Inclusion Criteria:\n\n* Patients awaiting a knee surgery (total knee arthroplasty (TKA), high tibial osteotomy (HTO), anterior cruciate ligament reconstruction(ACLR))\n\nExclusion Criteria:\n\n* Active infection\n* Atypical morphology and\u002For alignment of the lower limbs\n* Knee instability (other than secondary to ACL deficiency in patients awaiting ACLR)\n* Knee flexion contracture of 10 degrees or more\n* Knee flexion of less than 120 degrees","ALL","18 Years",{"count":75,"type":76},30,"ESTIMATED","INTERVENTIONAL",[79],"NA","Problem:\n\nCurrently, no system allows precise kinematic assessment of the knee and accurate guiding of orthopedic surgical actions in a minimally invasive fashion. However, such a system would prove useful in the clinical setting to improve the quality of surgical interventions at the knee.\n\nHypothesis:\n\nA novel knee kinematic assessment and surgical guidance tool using 3D personalized imaging and minimally invasive bony fixation allows precise kinematic assessment and surgical guidance in the routine clinical setting.\n\nObjectives :\n\n* Demonstrating the capacity of the system to precisely measure 3D knee kinematics\n* Quantifying the reproducibility of the kinematic measurements\n* Measuring the impact of knee surgical procedures on knee kinematics\n* Assessing the correlations between measured articular kinematics and clinical results after knee surgery\n* Integrating the novel measuring system to the surgical flow of three knee surgical procedures\n* Quantifying the precision and reproducibility of the surgical actions guided by the system\n* Comparing the clinical results of surgeries guided by the system to those performed with the traditional technique",[82,83,84,85,86],"Knee Osteoarthritis","Knee Instability","3D Knee Kinematics","Precision of Surgical Actions","Clinical Outcomes","NOT_YET_RECRUITING","2024-02-09",{"date":90,"type":91},"2024-02-12","ACTUAL",{"date":93,"type":76},"2025-12-01",{"date":95,"type":76},"2026-12-01",{"name":5,"class":6},1]