[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100357351":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":34,"responsibleParty":52,"collaborators":18,"id":55,"slug":18,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":18,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":18,"enrollmentInfo":63,"targetDuration":18,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":37,"whyStopped":18,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Northwestern University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Contextually-tailored Mobile Messages for Adherence","EXPERIMENTAL","AYA participants will be micro-randomized to receive contextually-tailored mobile messages designed to promote their oral chemotherapy adherence, with a 60% probability of receiving a contextually-tailored message each day.",[13],"Behavioral: ADAPTS (ADherence Assessments and Personalized Timely Support).",{"label":15,"type":16,"description":17,"interventionNames":18},"No messages","NO_INTERVENTION","All participants will also be micro-randomized to not receive messages on some days of the intervention (\\~40% of the time).",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","ADAPTS (ADherence Assessments and Personalized Timely Support).","ADAPTS is a mobile app intervention that integrates contextually-tailored mobile messages and decision rules about when to deliver the messages, with the ultimate goal of improving oral chemotherapy adherence in AYAs with acute lymphoblastic leukemia and lymphoma. AYA participants will be micro-randomized to receive messages on some days that are adapted to their current characteristics (e.g., mood, pain, location) and designed to promote adherence, and no messages (no intervention) on other days. Other features in the app include a medication calendar that syncs with the electronic medication monitor (eCAP) to track daily adherence. A caregiver version of ADAPTS is also available, providing daily surveys (but no randomized mobile messages) and the medication calendar so that dyads can mutually track adherence.",[9],[26],{"name":27,"affiliation":5,"role":28},"Alexandra M Psihogios, Ph.D.","PRINCIPAL_INVESTIGATOR",[30],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","312-503-3577","alex.psihogios@northwestern.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Robert H. Lurie Comprehensive Cancer Center, Northwestern University","RECRUITING","Chicago","Illinois","60611","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-87.65005,41.85003,{"lat":47,"lon":46},[50],{"name":51,"role":31,"phone":32,"phoneExt":18,"email":33},"Alexandra Psihogios, Ph.D.",{"type":28,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Alex Psihogios","Assistant Professor","100357351",false,"NCT03932903","Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia","Using Real Time Mobile Health Approaches to Understand and Promote Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia","AYA Inclusion Criteria:\n\n* Ages 14-29\n* Diagnosed with acute lymphoblastic leukemia (ALL) or lymphoma\n* In the maintenance phase, completed at least one cycle and has at least one month of maintenance therapy remaining.\n* Prescribed 6-mercaptopurine (6MP)\n* English language proficiency\n* For AYA \\<18, must have informed consent from their caregiver.\n\nAYA Exclusion Criteria:\n\n* Cognitive impairments that would limit ability to complete measures, determined by the medical team\n* Absence of inclusion criteria above.\n\nCaregiver Inclusion Criteria:\n\n* Nominated by the AYA as a primary caregiver involved in cancer care (can be a parent, relative, partner, friend)\n* English language proficiency\n\nCaregiver Exclusion Criteria:\n\n\\- Absence of inclusion criteria above.","ALL","14 Years",{"count":64,"type":65},60,"ESTIMATED","INTERVENTIONAL",[68],"NA","This is a small-scale micro-randomized clinical trial of a new mobile just-in-time adaptive intervention (JITAI) designed to promote oral chemotherapy adherence in adolescents and young adults (AYA) with acute lymphoblastic leukemia (ALL). The goals of this study are to determine intervention feasibility and acceptability.",[71,72],"Acute Lymphoblastic Leukemia","Lymphoblastic Lymphoma",[74,75,76,77,78],"Adherence","Adolescent","Young Adult","Mobile Health","Oncology","2026-06-29",{"date":81,"type":82},"2026-06-30","ACTUAL",{"date":84,"type":82},"2025-07-31",{"date":86,"type":65},"2027-08-31",{"name":5,"class":6},1]