Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 21
SponsorChildren's National Research Institute

About this trial

The purpose of this study is to prospectively collect specimens from pediatric patients with diffuse intrinsic pontine glioma or brainstem glioma, either during therapy or at autopsy, in order to characterize the molecular abnormalities of this tumor.

Eligibility criteria

Qualifiers

Patients of any age with clinical and radiologic diagnosis of diffuse intrinsic pontine glioma

Patients with other high-grade gliomas originating in the brainstem

Patients with focal gliomas (WHO grade I/II) of the brainstem

Disqualifiers

Patients with any type of infiltrative low grade (WHO grade I and II) or high grade glioma (WHO grade III and IV) originating outside the brainstem

Patients harboring primary brainstem tumors with other histologic diagnoses (e.g., PNET)

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

100 Participants
are grouped into 1 trial group