[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100222046":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":25,"responsibleParty":44,"collaborators":10,"id":48,"slug":10,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":10,"maxAge":55,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Scripps Translational Science Institute","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Index case",null,"Subjects who have died of sudden unexplained death",{"label":13,"type":10,"description":14,"interventionNames":10},"Biologically related family member","Biologically related family member of the deceased individual",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Sarah Topol, RN","CONTACT","858-784-2155","topol.sarah@scrippshealth.org",{"name":22,"role":18,"phone":23,"phoneExt":10,"email":24},"Emily Spencer, Phd","858-784-2029","egspence@scripps.edu",[26],{"facility":5,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"RECRUITING","La Jolla","California","92037","United States","US",{"type":34,"coordinates":35},"Point",[36,37],-117.2742,32.84727,{"lat":37,"lon":36},[40,41],{"name":17,"role":18,"phone":10,"phoneExt":10,"email":20},{"name":42,"role":18,"phone":10,"phoneExt":10,"email":43},"Emily Spencer, PhD","spencer.emily@scrippshealth.org",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Eric Topol, MD","PI, Director STSI","100222046",false,"NCT02168088","Molecular Autopsy Study","Molecular Autopsy for Sudden Cardiovascular Death","Inclusion Criteria:\n\n* Index case age between birth - 45 years\n* Clinical presentation of sudden \u002F unexplained death (believed to be cardiac in nature OR secondary to a massive unprovoked pulmonary embolism with no prior diagnosis of prothrombotic disease)\n\nExclusion Criteria:\n\n* Premature death secondary to murder, suicide or external causal event\n* Premature death thought secondary to known chronic comorbid medical condition\n* Premature death thought secondary to end-organ failure (kidney, liver, lung) other than heart\n* Previously diagnosed with hypertrophic cardiomyopathy (HCM)\n* Prior myocardial infarction (regardless of stenting or bypass)\n* Prior cerebrovascular accident (stroke or TIA)\n* History of open heart surgery (for any reason)\n* History of severe, untreated hypertensive heart disease\n* History of illicit drug use\n* History of heavy alcohol abuse\n* History of severe pulmonary disease\n* History of morbid obesity","ALL","45 Years",{"count":57,"type":58},100,"ESTIMATED","OBSERVATIONAL","This study seeks to incorporate genetic testing into the postmortem examination of cases of sudden unexplained death.",[62],"Sudden Unexplained Death",[64],"Sudden unexplained death","2025-01-15",{"date":67,"type":68},"2025-01-16","ACTUAL",{"date":70,"type":10},"2014-06",{"date":72,"type":58},"2030-06",{"name":5,"class":6},1]