[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100487377":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":17,"locations":23,"responsibleParty":42,"collaborators":10,"id":46,"slug":10,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":10,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},{"fullName":5,"class":6},"Dongzhimen Hospital, Beijing","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Phlegm-heat syndrome in ischemic stroke",null,"Phlegm-heat syndrome: the score of \"Phlegm-dampness syndrome\" ≥10 with the score of \"Internal fire syndrome\" ≥10 in Diagnostic Scale for Syndrome Elements of Ischemic Stroke",{"label":13,"type":10,"description":14,"interventionNames":10},"Non-phlegm-heat syndrome in ischemic stroke","Non-phlegm-heat syndrome: the score of \"Phlegm-dampness syndrome\" \\\u003C10 with the score of \"Internal fire syndrome\" \\\u003C10 in Diagnostic Scale for Syndrome Elements of Ischemic Stroke",{"label":16,"type":10,"description":10,"interventionNames":10},"Healthy subjects",[18],{"name":19,"role":20,"phone":21,"phoneExt":10,"email":22},"Xinxing Lai","CONTACT","8615901111280","new-star@163.com",[24],{"facility":25,"status":26,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Dongzhimen Hospital","RECRUITING","Beijing","Beijing Municipality","100700","China","CN",{"type":33,"coordinates":34},"Point",[35,36],116.39723,39.9075,{"lat":36,"lon":35},[39],{"name":40,"role":20,"phone":41,"phoneExt":10,"email":22},"Xinxing Lai, M.D.","15901111280",{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ying Gao","Professor","100487377",false,"NCT05626296","Molecular Network Characteristics of Phlegm-heat Syndrome in Ischemic Stroke Based on Multi-omics Integrated Analysis","Inclusion Criteria:\n\n* Acute ischemic stroke, were confirmed by magnetic resonance imaging (MRI).\n* Symptom onset within 72 hours.\n* Diagnosis of phlegm-heat syndrome or non-phlegm-heat syndrome.\n* Male or female ≥ 50 years and ≤ 80 years.\n* With written informed consent.\n\nExclusion Criteria:\n\n* Planned or already receiving intravenous thrombolysis or endovascular treatment.\n* Acute infectious diseases or acute exacerbations of chronic diseases within one month before enrollment.\n* Patients with previous stroke.\n* Renal or hepatic insufficiency, tumors, immune diseases, severe underlying diseases.\n* Other conditions that may affect the collection and evaluation of clinical information (e.g., severe aphasia, mental illness).",true,"ALL","50 Years","80 Years",{"count":56,"type":57},24,"ESTIMATED","OBSERVATIONAL","The molecular characteristics of ischemic stroke with phlegm-heat syndrome and candidate biomarkers were identified based on multi-omics data. The main purpose of this study is to validate the molecular characteristics and biomarkers of phlegm-heat syndrome in ischemic stroke, and to demonstrate the association of biomarkers with clinical outcomes.",[61],"Ischemic Stroke, Acute","2024-06-17",{"date":64,"type":65},"2024-06-20","ACTUAL",{"date":67,"type":65},"2022-11-14",{"date":69,"type":57},"2024-12-31",{"name":5,"class":6},1]