About this trial
Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost of over $250 million. Among ambulatory people with chronic stroke (PwCS), impaired balance is a common health concern that substantially limits mobility (those with the worst balance walk the least). This project will explore adaptive strategies employed by PwCS in balance challenging environments and if a novel gait training intervention using a robotic device to amplify a person's self-generated movements can improve walking balance. The development of effective interventions to increase walking balance among PwCS will positively impact Veterans' health, quality of life, and ability to participate in walking activities.
Eligibility criteria
Qualifiers
History of chronic stroke (more than 6 months post-stroke) with weakness on one side
Ability to ambulate over ground for 10 meters with or without a single cane, and/or ankle-foot orthosis
Ability to tolerate 10 minutes of standing
Disqualifiers
Presence of cognitive impairment (score of 22/30 on the Montreal Cognitive Assessment scale (MoCA))
Presence of aphasia (score of 71/100 on the Mississippi Aphasia Screening Test (MAST))
Excessive spasticity in lower limbs (score of > 3 on the Modified Ashworth Scale
Severe cardiovascular and pulmonary disease affecting gait and balance
Trial design
Treatments tested in this trial
- High intensity gait training in varying external environments
- Treadmill walking in varying external environments
Treatment groups
Sponsors and collaborators
VA Office of Research and Development
Lead sponsor
Northwestern University
Collaborator