About this trial
The aim of this study is to investigate the short-, medium-, and long-term effects of Mulligan Mobilization with Movement (MWM) added to an exercise program on pain, functionality, and biomechanical parameters in individuals with lateral elbow tendinopathy, compared to sham mobilization and exercise-only interventions.
The primary hypothesis is that the addition of true MWM to exercise will result in greater improvements in pain intensity, grip strength, pressure pain threshold, kinesiophobia, wrist joint position sense, and the mechanical properties of the extensor muscles compared to placebo (sham MWM) and exercise alone.
This study is designed as a three-arm randomized placebo-controlled trial. A total of 45 participants will be allocated to one of three groups: MWM plus exercise, sham MWM plus exercise, and exercise alone. Assessments will be conducted at baseline, immediately post-intervention, and at 3- and 6-month follow-ups.
The primary outcome measure is pain intensity. Secondary outcomes include functionality, grip strength, pressure pain threshold, kinesiophobia, wrist proprioception, and the mechanical properties of the extensor carpi radialis brevis muscle assessed using Myoton.
This study aims to determine the effects of manual therapy independent of placebo and to evaluate the sustainability of these effects over time. Additionally, by objectively assessing the mechanical and proprioceptive characteristics of the muscle-tendon unit alongside clinical outcomes, the study is expected to provide a novel contribution to the literature. The findings are anticipated to enhance the understanding of the mechanisms underlying conservative treatment approaches in lateral elbow tendinopathy and to support evidence-based clinical decision-making.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Inclusion Criteria
Age between 18 and 60 years
Presence of unilateral lateral elbow pain and tenderness for at least 3 months
Local tenderness over the lateral epicondyle
Disqualifiers
History of surgery around the elbow
History of elbow dislocation, fracture, or extensor tendon rupture
History of fracture of the humerus, ulna, or radius within the past year
Receipt of any treatment for LET within the past 6 months (e.g., physiotherapy, exercise, manual therapy, dry needling, orthosis)
Trial design
Parallel
Treatments tested in this trial
Mobilization with Movement (MWM)
Other interventionMWM is a manual therapy technique in which a therapist applies a sustained lateral glide to the radial head using a belt while the patient performs active gripping movements. The intervention is designed to restore pain-free movement by combining joint mobilization with functional activity.
Sham Mobilization with Movement (Sham MWM)
Other interventionSham MWM involves positioning the Mulligan belt in the same manner as the active intervention; however, no therapeutic joint mobilization force is applied. Participants perform active gripping movements while receiving a non-therapeutic simulation of mobilization.
Exercise
Other interventionThe exercise program targets the extensor carpi radialis brevis muscle and includes isometric, concentric, and eccentric strengthening exercises. Exercises are performed in a structured manner and progressed according to a pain-monitoring model allowing mild tolerable pain.
Treatment groups
Trial outcomes
Primary outcomes
Pain Intensity
Numeric Pain Rating Scale
Secondary outcomes
Pressure Pain Threshold
Algometer
Maximum Grip Strength
Hand Dynamometer
Pain-free Grip Strength
Hand Dynamometer
Functionality
Patient-Rated Tennis Elbow Evaluation
Sponsors and contacts
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Istanbul Kent University
Lead sponsor
Istanbul University - Cerrahpasa
Collaborator
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