[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616635":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":36,"centralContacts":40,"locations":23,"responsibleParty":46,"collaborators":23,"id":48,"slug":23,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":23,"enrollmentInfo":56,"targetDuration":23,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":69,"whyStopped":23,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":23},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients ventilated","EXPERIMENTAL","Baseline ventilator settings under pressure support",[13,14,15,16],"Procedure: Baseline","Procedure: Installation of high flow humidified air cannula","Procedure: Nasal air puffs","Procedure: propeller fan (FAN)",[18,24,28,32],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"PROCEDURE","Baseline","patient ventilated through the tracheostomy with initial ventilator settings",[9],null,{"type":19,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Installation of high flow humidified air cannula","Installation of high flow humidified air cannula with inspired oxygen fraction (FiO2) 21%",[9],{"type":19,"name":29,"description":30,"armGroupLabels":31,"otherNames":23},"Nasal air puffs","Nasal air puffs synchronized with the inspiratory time of the ventilator",[9],{"type":19,"name":33,"description":34,"armGroupLabels":35,"otherNames":23},"propeller fan (FAN)","Stand-alone fan at the bedside directed toward the face of the patient",[9],[37],{"name":38,"affiliation":5,"role":39},"Martin Dres, MD PhD","PRINCIPAL_INVESTIGATOR",[41],{"name":42,"role":43,"phone":44,"phoneExt":23,"email":45},"Martin DRES, MD PhD","CONTACT","+33142167809","martin.dres@aphp.fr",{"type":47,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100616635",false,"NCT07308171","Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients","MODUS","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Tracheostomy and mechanical ventilation\n3. Dyspnea ≥3\n4. Consent to participate\n5. Affiliation to health insurance\n\nExclusion Criteria:\n\n1. Agitation, delirium\n2. Continuous use of sedatives\n3. Patients under law protection\n4. Inmates\n5. Patients without health insurance\n6. Breastfeeding and pregnancy","ALL","18 Years",{"count":57,"type":58},24,"ESTIMATED","INTERVENTIONAL",[61],"NA","The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.",[64],"Ventilated Patients",[66,67,68],"Mechanical ventilation","Tracheostomy","Nasal stimulation","NOT_YET_RECRUITING","2026-01-27",{"date":72,"type":73},"2026-01-29","ACTUAL",{"date":75,"type":58},"2026-02",{"date":77,"type":58},"2027-02",{"name":5,"class":6}]