[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100334814":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":16,"responsibleParty":33,"collaborators":7,"id":37,"slug":7,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":40,"acronym":7,"eligibilityCriteria":41,"healthyVolunteers":38,"sex":42,"minAge":7,"maxAge":7,"enrollmentInfo":43,"targetDuration":46,"studyType":47,"phases":7,"briefSummary":48,"conditions":49,"keywords":7,"overallStatus":19,"whyStopped":7,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":60},{"fullName":5,"class":6},"University of Utah","OTHER",null,[9,14],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Josh Bonkowsky, MD, PhD","CONTACT","8012133599","joshua.bonkowsky@hsc.utah.edu",{"name":15,"role":11,"phone":12,"phoneExt":7,"email":7},"Courtney Chambers",[17],{"facility":18,"status":19,"city":20,"state":21,"zip":22,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"Primary Children's Hospital","RECRUITING","Salt Lake City","Utah","84113","United States","US",{"type":26,"coordinates":27},"Point",[28,29],-111.89105,40.76078,{"lat":29,"lon":28},[32],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},{"type":34,"investigatorFullName":35,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Josh Bonkowsky","Professor, Principal Investigator","100334814",false,"NCT03639285","Natural History, Diagnosis, and Outcomes for Leukodystrophies","Inclusion Criteria:\n\n* evidence by clinical exam, radiological findings, and\u002For testing, of an inherited leukodystrophy.\n* be able to travel to the leukodystrophy clinic (at Primary Children's Hospital, Salt Lake City, Utah);\n* be able to tolerate a general physical exam, and a neurological exam.\n\nExclusion Criteria:\n\n* unable to be evaluated at the University of Utah Hospital or Primary Children's Hospital;\n* refusal to sign study consent form;\n* evidence or finding of another non-genetic cause of their condition;\n* Persons with known white matter disease or lesions related to: birth injury or prenatal injury, multiple sclerosis, trauma, infection, immunization, or post-infectious effects (e.g. ADEM- acute disseminated encephalomyelitis), metabolic disturbance (e.g. Central pontine myelinolysis), neoplasms, primary rheumatologic diseases (e.g. Systemic lupus erythematosis), stroke, hypoxic-ischemic injury, drug or toxin effect, seizures, or endocrine disturbance.","ALL",{"count":44,"type":45},600,"ESTIMATED","20 Years","OBSERVATIONAL","The goals of this protocol is to diagnose, care for, and understand the clinical histories and outcomes of people with leukodystrophies.",[50],"Leukodystrophy","2026-01-11",{"date":53,"type":54},"2026-01-13","ACTUAL",{"date":56,"type":54},"2007-01-19",{"date":58,"type":45},"2050-12-31",{"name":5,"class":6},1]