[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100486434":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":42,"responsibleParty":59,"collaborators":25,"id":62,"slug":25,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":25,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Icahn School of Medicine at Mount Sinai","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Real fNIRS Neurofeedback Arm","EXPERIMENTAL","Participants assigned to the experimental arm will see their true, real-time brain activation (i.e., active real-time neurofeedback) during the neurofeedback session. This activation will be displayed to the participant as a thermometer that will increase as brain activation in the target region increases.",[13],"Other: Real fNIRS Neurofeedback",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham-Control fNIRS Neurofeedback Arm","SHAM_COMPARATOR","Participants assigned to the sham-control arm will see false feedback (or a fake signal) that is not connected to their right vlPFC activation during the neurofeedback session.",[19],"Other: Sham-Control fNIRS Neurofeedback",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Real fNIRS Neurofeedback","Participants will be instructed to use real-time fNIRS neurofeedback to non-invasively regulate neural activation associated with symptoms in individuals with bulimia nervosa. During the training, participants will view images on a computer screen, listen to sounds, and consume a shake.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Sham-Control fNIRS Neurofeedback","Participants will be instructed to use sham real-time fNIRS neurofeedback to non-invasively regulate neural activation associated with symptoms in individuals with bulimia nervosa. During the training, participants will view images on a computer screen, listen to sounds, and consume a shake.",[15],[31],{"name":32,"affiliation":5,"role":33},"Laura A Berner, Ph.D.","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Sila Sozeri, B.A.","CONTACT","(212) 201-2679","sila.sozeri@mssm.edu",{"name":32,"role":37,"phone":25,"phoneExt":25,"email":41},"laura.berner@mssm.edu",[43],{"facility":44,"status":45,"city":46,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Center for Computational Psychiatry at the Icahn School of Medicine at Mount Sinai","RECRUITING","New York","10027","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-74.00597,40.71427,{"lat":54,"lon":53},[57],{"name":58,"role":33,"phone":25,"phoneExt":25,"email":25},"Laura A. Berner",{"type":33,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Laura Berner","Assistant Professor","100486434",false,"NCT05614024","Neurofeedback During Eating for Bulimia Nervosa","Neurofeedback During Eating: A Novel Mechanistic Treatment for Bulimia Nervosa","Inclusion criteria:\n\n* Female\n* Aged 18 to 45 years\n* Meet diagnostic criteria for bulimia nervosa\n* Current body mass index greater than or equal to 18.5kg\u002Fm2 but under 30kg\u002Fm2\n* English-speaking\n\nExclusion criteria:\n\n* Ongoing medical treatment, major medical condition, or psychiatric disorder that may interfere with study variables or participation\n* Current psychotherapy focused primarily on eating disorder symptoms\n* Pregnancy or planned pregnancy, or lactation during the study period\n* Allergy to ingredients in the standardized meal or in the shake","FEMALE","18 Years","45 Years",{"count":72,"type":73},30,"ESTIMATED","INTERVENTIONAL",[76],"NA","The purpose of this study is to examine the effects of noninvasive prefrontal cortex (PFC) neurofeedback during eating in women with bulimia nervosa (BN) using a wearable brain imaging device, functional near-infrared spectroscopy (fNIRS). The investigators will examine how this training may influence inhibitory control and BN symptoms.",[79],"Bulimia Nervosa","2026-01-28",{"date":82,"type":83},"2026-01-30","ACTUAL",{"date":85,"type":83},"2024-05-13",{"date":87,"type":73},"2027-12",{"name":5,"class":6},1]