[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100515061":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":38,"locations":44,"responsibleParty":65,"collaborators":42,"id":68,"slug":42,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":42,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":42,"enrollmentInfo":77,"targetDuration":42,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":42,"overallStatus":46,"whyStopped":42,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University of California, Berkeley","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"TranS-C+MSI","EXPERIMENTAL","Transdiagnostic Intervention for Sleep and Circadian Dysfunction will be combined with the Memory Support Intervention",[13,14],"Behavioral: Memory Support Intervention","Behavioral: Transdiagnostic Intervention for Sleep and Circadian Dysfunction",{"label":16,"type":17,"description":18,"interventionNames":19},"TranS-C alone","ACTIVE_COMPARATOR","The Transdiagnostic Sleep and Circadian Intervention will be delivered alone",[14],[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Memory Support Intervention","The Memory Support Intervention is designed to improve patient memory for treatment and involves a series of specific procedures that support the encoding and retrieval stages of episodic memory. The memory support strategies are proactively, strategically and intensively integrated into treatment-as-usual to support encoding. Memory support is delivered alongside each 'treatment point', defined as a main idea, principle, or experience that the treatment provider wants the patient to remember or implement as part of the treatment.",[9],[27],"MSI",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Transdiagnostic Intervention for Sleep and Circadian Dysfunction","TranS-C aims to provide one protocol to treat a range of sleep and circadian problems because sleep and circadian problems are often not so neatly categorized and because the existing research provides few guidelines to treat more complex patients.",[16,9],[33],"TranS-C",[35],{"name":36,"affiliation":5,"role":37},"Allison Harvey, PhD","PRINCIPAL_INVESTIGATOR",[39],{"name":36,"role":40,"phone":41,"phoneExt":42,"email":43},"CONTACT","5106427138",null,"aharvey@berkeley.edu",[45],{"facility":5,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Berkeley","California","94720-1650","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-122.27275,37.87159,{"lat":56,"lon":55},[59,61],{"name":36,"role":40,"phone":60,"phoneExt":42,"email":43},"510-642-7138",{"name":62,"role":40,"phone":63,"phoneExt":42,"email":64},"Nena Salazar","‪(925) 421-0083‬","n.salazar@berkeley.edu",{"type":37,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"Allison Harvey","Professor","100515061",false,"NCT05986604","NIA_Improving Function and Well-being by Improving Patient Memory: Transdiagnostic Sleep and Circadian Treatment","NIA_Improving Sleep and Circadian Functioning, Daytime Functioning, and Well-being for Midlife and Older Adults by Improving Patient Memory for a Transdiagnostic Sleep and Circadian Treatment","Inclusion criteria:\n\n1. Aged 50 years and older;\n2. English language fluency;\n3. Experiencing a mobility impairment;\n4. Low income;\n5. Exhibit a sleep or circadian disturbance as determined by endorsing 4 \"quite a bit\" or 5 \"very much\" (or the equivalent for reverse scored items) on one or more PROMIS-SD questions.\n6. 25-30 on the Montreal Cognitive Assessment, as a negative screen for cognitive impairment.\n7. Able\u002Fwilling to give informed consent.\n\nExclusion criteria:\n\n1. Severe untreated sleep disordered breathing (AHI\\>30) or moderate untreated sleep disordered breathing with severe daytime sleepiness (AHI of 15-30 and Epworth Sleepiness Scale \\>10);\n2. Medical conditions that prevent a participant from comprehending and following the basic tenants of treatment (e.g., dementia) or that interfere with sleep in a manner that can't be addressed by a cognitive behavioral treatment (e.g., the Structured Clinical Interview for Sleep Disorders will be used to screen for narcolepsy, REM sleep behavior disorder) or that may preclude full participation (e.g., receipt of end of life care);\n3. Homelessness;\n4. Night shift work \\>2 nights per week in the past 3 months;\n5. Substance abuse\u002Fdependence only if it makes participation in the study unfeasible;\n6. Suicide risk sufficient to preclude treatment on an outpatient basis.",true,"ALL","50 Years",{"count":78,"type":79},178,"ESTIMATED","INTERVENTIONAL",[82],"NA","Mental illness is often chronic, severe, and difficult to treat. Though there has been significant progress towards establishing effective and efficient interventions for psychological health problems, many individuals do not gain lasting benefits from these treatments. The Memory Support Intervention (MSI) was developed utilizing existing findings from the cognitive science literature to improve treatment outcomes. In this study, the investigators aim to conduct an open trial that includes individuals 50 years and older to assess if a novel version of the Memory Support Intervention improves sleep and circadian functioning, reduces functional impairment, and improves patient memory for treatment.",[85,86,87],"Sleep Disorder","Circadian Dysregulation","Memory Impairment","2025-11-18",{"date":90,"type":91},"2025-11-24","ACTUAL",{"date":93,"type":91},"2024-01-04",{"date":95,"type":79},"2028-07-28",{"name":5,"class":6},1]