Nutrition-based Interventions to Prevent Cognitive Decline

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age55-85
SponsorInstituto de Saude Publica da Universidade do Porto

About this trial

This study intends to evaluate the feasibility and the effectiveness of an innovative and integrated nutrition-based intervention addressing key modifiable risk factors for dementia while meeting participants' preferences for nutrition-related sessions. The intervention will include lifestyle group sessions regarding nutrition education and physical activity, individualized cognitive training at home, as well as clinical nutrition consultations.

Eligibility criteria

Qualifiers

Aged from 55 to 85 years old;

At least 4 years in the regular school system;

Higher individual risk for dementia defined as a score ≥6 points on the Cardiovascular Risk Factors, Aging and Dementia Dementia Risk Score (CAIDE).

Disqualifiers

Montreal Cognitive Assessment (MoCA) score lower than the validated cutoff points defined as 2 standard deviations below the normative reference value for the corresponding age and education in the Portuguese population;

Having a medical condition limiting the participation in the intervention (e.g., blindness, amputation…);

Lack of autonomy in daily activities;

Diagnosis of dementia or major incapacity.

Trial design

Treatments tested in this trial

  • Nutrition-related lifestyle group sessions
  • Cognitive training
  • Clinical nutrition consultations

Treatment groups

120 Participants
are divided into 2 treatment groups