[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631227":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":56,"collaborators":25,"id":59,"slug":25,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Fu Jen Catholic University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Probiotic group","EXPERIMENTAL","Received standard postoperative care with probiotic supplementation",[13],"Other: probiotic supplementation intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo group","PLACEBO_COMPARATOR","Received standard postoperative care with placebo supplementation",[19],"Other: Placebo supplementation intervention",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"probiotic supplementation intervention","probiotic supplementation will be administered, while participants continue undergoing standard postoperative care",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Placebo supplementation intervention","Undergo routine standard postoperative care with placebo intervention",[15],[31],{"name":32,"affiliation":5,"role":33},"Ke-Yun Chao, PhD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","+886-905-301-879","C00152@mail.fjuh.fju.edu.tw",[40],{"facility":41,"status":42,"city":43,"state":25,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Fu Jen Catholic University Hospital, Fu Jen Catholic University","RECRUITING","New Taipei City","24352","Taiwan","TW",{"type":48,"coordinates":49},"Point",[50,51],121.45703,25.06199,{"lat":51,"lon":50},[54],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":55},"ck_qq@hotmail.con",{"type":33,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Ke-Yun, Chao","Assistant Professor","100631227",false,"NCT07497932","Nutritional Effects in Cardiovascular Surgery","Nutritional Intervention in the Modulation of Postoperative Metabolism in Cardiovascular Surgery","Inclusion Criteria:\n\n* Scheduled to undergo cardiovascular surgery\n* Completed preoperative clinical and imaging evaluations\n* Willing to provide informed consent\n* Willing to receive potential probiotic supplementation\n\nExclusion Criteria:\n\n* Use of antibiotics, probiotics, or other treatments affecting gut microbiota within 4 weeks\n* History of major gastrointestinal disease","ALL","50 Years","80 Years",{"count":69,"type":70},30,"ESTIMATED","INTERVENTIONAL",[73],"NA","This study aims to investigate the distribution of gut microbiota-derived metabolites, and to evaluate whether postoperative nutritional intervention can modulate the gut-heart metabolic axis, thereby improving metabolic profiles and clinical outcomes.",[76,77],"Cardiovascular Surgery","Cardiovascular Disease",[79,80,81,82,83],"Gut microbiota-derived metabolites","Metabolomics","Cardiovascular disease","Nutritional intervention","Mass spectrometry","2026-03-23",{"date":86,"type":87},"2026-03-27","ACTUAL",{"date":89,"type":87},"2026-03-19",{"date":91,"type":70},"2026-12-31",{"name":5,"class":6},1]