Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorHospital de Clinicas de Porto Alegre
About this trial
The goal of this clinical trial is to evaluate whether a dietitian-guided nutritional intervention can improve constipation symptoms in people with Parkinson's disease (PD). The main questions it aims to answer are:
* Can a dietitian-guided nutritional intervention increase the number of weekly bowel movements in individuals with PD and functional constipation? * Can this intervention positively influence gut microbiota composition, dietary intake, and nutritional status?
Researchers will compare the intervention group to a control group that will receive general dietary guidance only after the study period, to see if the intervention leads to improvements in bowel function and related health outcomes.
Participants will:
* Follow a diet plan developed by a dietitian, based on dietary reference intakes and tailored to the needs of individuals with PD and constipation * Participate in follow-up sessions with the dietitian for 3 months * Complete assessments at baseline, midpoint, and end of the intervention to evaluate bowel function, constipation symptoms, gut microbiota, nutritional status, and diet quality
Eligibility criteria
Qualifiers
Adults with a previous diagnosis of Parkinson's disease
On a stable dose of levodopa for at least 3 months
Diagnosis of Functional Constipation by the Rome IV protocol
Disqualifiers
Diagnosis of atypical or secondary parkinsonism
Hoehn and Yahr stage greater than 2
Presence of severe neurological or psychiatric disorders that impair the ability to participate in study procedures
Previous diagnosis of dementia
Trial design
Treatments tested in this trial
- Dietitian-Guided Nutritional Intervention
Treatment groups
54 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov