Objective Concussion Assessment Using MRI and Metabolomics

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age9-50
SponsorSt. Joseph's Healthcare Hamilton

About this trial

Mild traumatic brain injury (mTBI), also referred to as concussions, affect millions of people around the world and can cause harmful long term effects. Unfortunately, concussions can be hard to diagnose and many people have lasting post-concussion symptoms such as headaches, difficulty concentrating, and light sensitivity. Recent studies have shown that advanced magnetic resonance imaging (MRI) techniques can identify subtle brain changes caused by a concussion. This study aims to track concussions over time measuring MRI brain scans and post-concussion symptoms to gain a better understand how the brain is affected in comparison to symptoms.

Eligibility criteria

Qualifiers

Aged between 9-50

Recently sustained a concussion (within the last 2 weeks)

Disqualifiers

Aged 8 and younger or 51 and older

Unable to provide consent (e.g., poor English language skills, etc.)

History of liver or kidney disease

Pacemaker

Trial design

Treatments tested in this trial

  • Magnetic resonance imaging (MRI)
  • Urine and saliva samples
  • Questionnaires

Treatment groups

100 Participants
are divided into 2 treatment groups

Sponsors and collaborators

St. Joseph's Healthcare Hamilton

Lead sponsor

McMaster University

Collaborator