About this trial
This study is a multicenter, prospective, and observational clinical study aimed at exploring whether the 3-year DFS in the Huaier group is not inferior to the control group receiving standard platinum dual-drug chemotherapy.
Eligibility criteria
Qualifiers
18 years old ≤ age ≤ 75, regardless of gender.
Confirmed as non-small cell lung cancer by histopathology, with pathological staging of stage Ⅱ-ⅢA.
Received radical R0 resection of lung cancer within 2 months before enrollment, and did not receive any postoperative adjuvant therapy or preoperative neoadjuvant therapy.
ECOG(Eastern Cooperative Oncology Group)score:0-2.
Disqualifiers
Known to be allergic to the components of Huaier granules or avoid or use Huaier granules with caution (Huaier group).
Those who have difficulty swallowing, complete or incomplete gastrointestinal obstruction, active gastrointestinal bleeding, perforation, and other causes of difficulty in taking oral medication.
Non-small cell lung cancer patients who plan to receive targeted therapy, immunotherapy, chemotherapy combined with immunotherapy, radiotherapy, synchronous radiotherapy and chemotherapy during the study period.
The patient has a history of other new malignant tumors within 5 years.
Trial design
Treatments tested in this trial
- Huaier granule
- Control
Treatment groups
Sponsors and collaborators
Liaoning Cancer Hospital & Institute
Lead sponsor
LinkDoc Technology (Beijing) Co. Ltd.
Collaborator
Huazhong University of Science and Technology
Collaborator