[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644886":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":7,"locations":7,"responsibleParty":8,"collaborators":10,"id":14,"slug":7,"hasResults":15,"nctId":16,"briefTitle":17,"officialTitle":18,"acronym":19,"eligibilityCriteria":20,"healthyVolunteers":15,"sex":21,"minAge":22,"maxAge":7,"enrollmentInfo":23,"targetDuration":7,"studyType":26,"phases":7,"briefSummary":27,"conditions":28,"keywords":7,"overallStatus":30,"whyStopped":7,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":7},{"fullName":5,"class":6},"Prenosis, Inc.","INDUSTRY",null,{"type":9,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[11],{"name":12,"class":13},"Biomedical Advanced Research and Development Authority","FED","100644886",false,"NCT07675265","Observational, Non-interventional Biomarker and Endotyping Study","Observational Biomarker Study for the Evaluation of Response and Validation of Endotypes in Acute Respiratory Distress Syndrome","OBSERVE-ARDS","Inclusion Criteria:\n\n* Age ≥18 years\n* ARDS Diagnosis (New Global Definition of ARDS)\n* Timing: Acute onset within 7 days\n* Radiology: Bilateral pulmonary opacities\n* Hypoxia:\n\nNon-intubated ARDS: PaO2:FIO2\\\u003C300mmHg or SpO2:FIO2\\\u003C315 (if SpO2\\\u003C97%) on HFNO with flow of \\>30 L\u002Fmin or NIV\u002FCPAP with at least 5 cm H2O end-expiratory pressure; or Intubated ARDS: PaO2:FIO2\\\u003C300 mm Hg or SpO2:FIO2\\\u003C315 (if SpO2\\\u003C97%)\n\n* ICU admission\n* Enrolled within 72 hours of meeting inclusion criteria\n\nExclusion Criteria:\n\n• Primary cardiogenic pulmonary edema","ALL","18 Years",{"count":24,"type":25},1200,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to establish a centralized ARDS biorepository of longitudinal biospecimens and harmonized clinical data, develop unsupervised, therapy-agnostic endotyping algorithms, and develop unsupervised, therapy-specific treatment-prediction algorithms over a 24 month period.",[29],"ARDS (Acute Respiratory Distress Syndrome)","NOT_YET_RECRUITING","2026-06-23",{"date":33,"type":34},"2026-06-30","ACTUAL",{"date":36,"type":25},"2026-07",{"date":38,"type":25},"2029-03",{"name":5,"class":6}]