Observational Study on the Impact of Herpes Zoster Vaccine on the Incidence of Herpes Zoster and Survival in Lung Cancer Patients

ConditionLung Cancer
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThe First Affiliated Hospital of Guangzhou Medical University

About this trial

To evaluate the impact of herpes zoster vaccine on the incidence of herpes zoster and survival in lung cancer patients, and to explore its preventive effect and safety.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

1.Male or female patients >=18 years of age; 2.Histological diagnosis of NSCLC, including both non-small cell lung cancer and small cell lung cancer, regardless of whether they are in the early, locally advanced stage or advanced stage, and regardless of whether they have received surgery, radiotherapy, chemotherapy or other treatments; 3. Never received herpes zoster vaccine

Disqualifiers

Patients having other factors that preventing researchers from enrollment them.

Trial population

Lung cancer patients can receive or not receive the herpes zoster vaccine

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • herpes zoster vaccine

    Biological/Vaccine

    Receive the herpes zoster vaccine; Do not receive the herpes zoster vaccine

Treatment groups

500 Participants
are divided into 2 treatment groups
Group A: Vaccination group1 intervention
Group B: Unvaccinated group0 interventions

Trial outcomes

Primary outcomes

1

The incidence of herpes zoster at 12 months

During the 12-month follow-up period, the incidence of herpes zoster in lung cancer patients was evaluated through regular clinical examinations, imaging tests, and laboratory tests.

Time frame
12 months
2

Incidence of herpes zoster

The proportion of lung cancer patients who developed herpes zoster during the study period.

Time frame
24 months

Secondary outcomes

1

Survival rate

The survival rate of lung cancer patients within a specific time period (such as 1 year, 2 years, or 5 years).

Time frame
5 years

Other outcomes

1

Lung cancer-related complications

Severity of herpes zoster and incidence of complications (e.g., postherpetic neuralgia)

Time frame
5 years
2

Length of hospital stay

Record the number of days of hospitalization for patients hospitalized due to herpes zoster

Time frame
5 years
3

Hospitalization rate

The proportion of patients hospitalized due to herpes zoster or other related complications.

Time frame
5 years
4

Immune response

The immune response (such as antibody levels) of patients after vaccination is evaluated through serological testing.

Time frame
5 years

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

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