OCT Versus Angiography for Culprit Lesion Revascularization in Acute Myocardial Infarction PatiEnts
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19+
SponsorChonnam National University Hospital
About this trial
The aim of the study is to compare clinical outcomes between optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).
Eligibility criteria
Qualifiers
Subject must be at least 19 years of age
Acute ST-segment elevation myocardial infarction (STEMI)
Primary percutaneous coronary intervention (PCI) in < 12 h after the onset of symptoms for STEMI patients
Subject is able to verbally confirm understandings of risks, benefits and treatment alternatives of receiving invasive physiologic evaluation and PCI and he/she or his/her legally authorized representative provides written informed consent prior to any study related procedure.
Disqualifiers
Target lesions not amenable for PCI by operators' decision
Ostial lesions located in left main vessel or right coronary artery (left main body or distal bifurcation lesions can be enrolled by operator's discretion)
Creatinine clearance ≤30 ml/min/1.73 m2 and not on dialysis (chronic dialysis dependent patients are eligible for enrolment regardless of creatinine clearance)
Cardiogenic shock (Killip class IV) at presentation
Trial design
Treatments tested in this trial
- Angiography-guided PCI group
- Optical coherence tomography-guided PCI group
Treatment groups
1,500 Participants
are divided into 2 treatment groupsSponsors and collaborators
Chonnam National University Hospital
Lead sponsor
Samsung Medical Center
Collaborator
Source ClinicalTrials.gov