About this trial
This prospective longitudinal cohort study will enroll adults aged 50 years and older to characterize olfactory dysfunction in aging. Participants will undergo comprehensive olfactory testing, cognitive assessment, biomarker collection, and imaging to identify clinically relevant phenotypes based on anatomic site of dysfunction. The study will also evaluate the impact of olfactory dysfunction on quality of life and identify baseline factors associated with changes in olfactory function over time.
Eligibility criteria
Qualifiers
Age: 50 years or older
Ability to follow instructions and understand consent process in English
Adequate visual, auditory, or motor functioning to complete items in the test battery or availability of assistance or assist devices to complete tasks
Disqualifiers
None
Trial design
Treatments tested in this trial
- Clinical and Biomarker Assessments
Treatment groups
Sponsors and collaborators
Medical University of South Carolina
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborator