Online Interplay Between Deciding and Acting With Mild Cognitive Impairment
ConditionMild Cognitive Impairment
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age45-90
SponsorUniversity of Delaware
About this trial
The investigators aim to understand the interplay and neural structures involved with decision--making and movement for participants with mild cognitive impairment. Rapidly deciding and acting becomes bottlenecked with mild cognitive impairment and Alzheimer's, leading to detrimental outcomes such as falling and car crashes. The investigators work will have a tangible impact by discovering sensitive biomarkers to detect disease onset and pave the way for informed and effective neurorehabilitation.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
age 45 - 90 years
Perfect or corrected vision
Ability to reach
Neurotypical Age-Matched control participants - No history of neurological disorders or injury.
Disqualifiers
Any injury or condition that impacts reaching
Traumatic brain injury, such as concussion, in the last 6 months.
Neurotypical Age-Matched control participants: Modified Telephone Interview for Cognitive Status (TICS-m) score < 34
Mild Cognitive Impairment participants: Modified Telephone Interview for Cognitive Status (TICS-m) score > 34
Trial design
Design model
Single group
Treatments tested in this trial
Reaching Movements
Behavioralparticipants will perform a perceptual decision making task while moving their hand.
Treatment groups
60 Participants
are divided into 2 treatment groupsGroup A: Reaching taskExperimental treatment 1 intervention
Group B: Reaching TaskActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Reaching Movements
Hand position will be recorded throughout each trial during the behavioral task
Time frame
through study completion, an average of 1 year2
Change in brain mechanical properties
Investigators are assessing change in brain structure through mechanical properties
Time frame
through study completion, an average of 1 yearSecondary outcomes
1
Decision Time
Decision time will be calculated on each trial during the behavioral task
Time frame
through study completion, an average of 1 yearSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Delaware
Lead sponsor
National Institutes of Health (NIH)
Collaborator
National Institute of General Medical Sciences (NIGMS)
Collaborator
Source ClinicalTrials.gov