[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100384716":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":34,"responsibleParty":51,"collaborators":18,"id":53,"slug":18,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":18,"maxAge":61,"enrollmentInfo":62,"targetDuration":18,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":18,"overallStatus":36,"whyStopped":18,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Medical University of Vienna","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention","EXPERIMENTAL","lung recruitment maneuvers performed every twelve hours during HFOV",[13],"Procedure: regular lung recruitment",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","no regular lung recruitment maneuvers during HFOV",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","regular lung recruitment","stepwise oxygenation-guided lung recruitment at regular (twelve hours) intervals during high frequency oscillation ventilation",[9],[26],{"name":27,"affiliation":5,"role":28},"Tobias Werther","PRINCIPAL_INVESTIGATOR",[30],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","+4314040032320","tobias.werther@meduniwien.ac.at",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Vienna","State of Vienna","1090","Austria","AT",{"type":43,"coordinates":44},"Point",[45,46],16.37208,48.20849,{"lat":46,"lon":45},[49],{"name":27,"role":31,"phone":50,"phoneExt":18,"email":33},"014040032320",{"type":28,"investigatorFullName":27,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Principal Investigator","100384716",false,"NCT04289324","Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants","Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Extremely Preterm Infants - A Single Center Randomized Controlled Trial","OPEN4HFOV","Inclusion Criteria: Preterm infants\n\n* born below 28 weeks of gestational age\n* not older than 29 weeks of postmenstrual age\n* receive HFOV\n\nExclusion Criteria:\n\n* known congenital anomalies of the heart, of the lung, and\u002For of the central nervous system\n* known chromosomal abnormalities\n* participation in other intervention trials","ALL","8 Weeks",{"count":63,"type":64},36,"ESTIMATED","INTERVENTIONAL",[67],"NA","To assess whether stepwise oxygenation-guided lung recruitment at regular intervals reduces the oxygen saturation index (OSI = Mean Airway Pressure × Fraction of inspired Oxygen × 100 \u002F peripheral Oxygen Saturation, OSI = MAPxFiO2x100\u002FSpO2) averaged over high frequency oscillation ventilation (HFOV) time in extremely preterm infants.",[70,71,72],"High Frequency Oscillation Ventilation","Extreme Prematurity","Lung Injury, Acute","2024-11-18",{"date":75,"type":76},"2024-11-20","ACTUAL",{"date":78,"type":76},"2020-02-25",{"date":80,"type":64},"2025-12-31",{"name":5,"class":6},1]