Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-89
SponsorAllegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

About this trial

This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery. This project is considered "Research" and participation is voluntary. Upon enrollment in this study, the research team will collect data from the patient's medical records. The patient will undergo all of the normal testing and procedures required pre-operatively (standard of care). The study team will then randomly assign the patient (like a flip of a coin) to one of three different study arms for pain management during surgery:

1. Laparoscopic Transversus Abdominis Plane Block (LapTAP) with Local Anesthetic (LA) 2. Laparoscopic Transversus Abdominis Plane Block (LapTAP) only 3. Local Anesthetic (LA) only The patient will receive standard pre- and post-operative care according to clinical guidelines (routine care). The study team will collect information from the patient's medical record for the first 24 hours after their surgery and upon discharge. This information will include pain scores, amount of medication required, any side effects the patient may have experienced, and satisfaction with pain control. Participation in the study will end upon discharge from the hospital.

Eligibility criteria

Qualifiers

Male and female patients age ≥ 18 - 89

Patients scheduled for elective (clinically indicated) hepatic, gastric, biliary, pancreatic, gynecologic, colorectal, other GI Minimally invasive oncologic surgery.

Patients who have provided informed consent to participate in the study.

Patients with an American Society of Anesthesiologists (ASA) physical status classification of I, II, or III.

Disqualifiers

Patients age less than 18 or ≥ 90

Pre-existing hepatic dysfunction, cirrhosis

Patients with an ASA classification of IV or higher.

Patients with chronic pain disorders or on long-term opioid or analgesic therapy.

Trial design

Treatments tested in this trial

  • Local Anesthesia
  • Laparoscopic Transversus Abdominis Plane block

Treatment groups

48 Participants
are divided into 3 treatment groups