Acoustic overexposure can induced temporary or hearing loss. Usually hearing loss is associated with cochlear cell damages. Recently, a new pathological entity was described and called "hidden hearing loss". In animal model, the histopathology revealed a selective reduction in the number of auditory fibers, resulting in a decrease in the amplitude of wave I of the auditory brainstem response. Electrocochleography (Ecog) is a method for recording the electrical potentials of the cochlea (e.g. wave I). In clinical routine, Ecog is performed invasively with sedation or local anesthesia. Actually, a non invasive approach could be perform but it seems necessary to optimize this method and to define reference values in healthy volunteers.
Between 18 and 55 years old
be affiliated to a social security system
understand (oral and written) of the French language
be a qualified hearing with normal tympanogram and audiogram
have a complaint of hearing
have a exposure to noise (professional and/or activities)
refusal to participate in the study
have ear infections and/or ENT medical history
Single group
Electrocochleography, electrophysiology thet for analyse the wave I generated by the auditory pathways
Diagnostic testElectrocochleography is a technique that analyses the functionality of inner ear.
Latency of wave I by electrocochleography
The wave I analyzed at electrocochleography will allow to obtain the latency (milliseconds) of action potential (AP)
Latency of wave I by electrocochleography
The wave I analyzed at electrocochleography will allow to obtain the latency (milliseconds) of action potential (AP)
Hearing thresholds in decibels
The audiometry will make it possible to obtain the hearing thresholds in decibels for all frequency of 250, 500, 750, 1000, 1500, 2000, 3000, 4000, 6000, 8000, 9000, 10000, 11200, 12500 and 14000 Hz.
Acoustic reflex thresholds in decibels
The acoustic reflex allows to evaluate the trigger threshold in decibels of the reflex for the frequencies 500, 1000, 2000, 4000Hz.
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University Hospital, Clermont-Ferrand
Lead sponsor
Laboratory of Neurosensory Biophysics - UMR INSERM 1107.
Collaborator
Foundation of Gueules Cassées
Collaborator
Region of Auvergne-Rhône-Alpes
Collaborator
