Optimization of MRI Sequences Used in the Study of Neurodegenerative Diseases
ConditionMemory Disorders
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital, Caen
About this trial
The Inserm NeuroPresage team has been using MRI for more than 20 years in the study of normal ageing and memory pathologies to further the understanding and the characterization of early diagnosis and the cerebral substrates of cognitive deficits in patients, particularly in the context of neurodegenerative diseases.
Two years ago, a new 3T MRI camera was installed at the Cyceron centre. It is more efficient and should make it possible to obtain better quality images and/or to reduce the time required to acquire these images.
In this context, it seems important to test the different sequences that we classically use in our studies, or that we plan to implement in our next studies (learning and text retrieval fMRI task), in order to optimize them, with a view to integrating them in our future studies.
Eligibility criteria
Qualifiers
Healthy volunteers of legal age
Affiliation with a social security scheme or beneficiary of such a scheme
Signing of the protocol informed consent
For women of childbearing age or capacity, a urine pregnancy test before inclusion
Disqualifiers
Protected persons in accordance with articles L. 1121-5 to L.1121-8 of the Public Health Code: protected adults, pregnant and nursing women
Presence of contraindications to MRI examination without contrast agents injection
Presence of a chronic neurological or psychiatric condition (including substance use disorder)
History of brain disease (vascular, degenerative, malformative, tumour, or head trauma with loss of consciousness for more than one hour)
Trial design
Treatments tested in this trial
- MRI sequences testing
Treatment groups
40 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov