[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541894":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":33,"centralContacts":37,"locations":47,"responsibleParty":65,"collaborators":42,"id":67,"slug":42,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":42,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":42,"enrollmentInfo":75,"targetDuration":42,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":49,"whyStopped":42,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Wake Forest University Health Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SENNA","EXPERIMENTAL","Group A participants will be prescribed oral senna (Senokot; Atlantis Consumer Healthcare Inc., Bridgewater, NJ) 8.6mg tablets and be instructed to start with two tablets on the morning of Post Operative Day (POD)#1. Participant will continue taking two tablets on the daily. If no bowel movement on the morning of POD#3 participant may take 2 tablets in the morning and another 2 tablets that evening. The same can be replicated on POD#4. If no bowel movement on the morning of POD#5 participant may take magnesium hydroxide (Phillips' Milk of Magnesia; Bayer AG, Leverkusen, Germany) 30 mL by mouth and need to call the urology clinic for further instruction.",[13],"Dietary Supplement: Senna Tab",{"label":15,"type":10,"description":16,"interventionNames":17},"DULCOLAX","Group B participants will be prescribed bisacodyl rectal (Dulcolax Suppository; Sanofi S.A., Paris, France) 1 suppository to be placed rectally on the morning of Post Operative Day (POD)#1. Participant will continue placing a nightly rectal suppository until their first bowel movement. If no bowel movement by the morning of POD#5 participant may take magnesium hydroxide (Phillips' Milk of Magnesia; Bayer AG, Leverkusen, Germany) 30 mL by mouth and need to call the clinic for further instruction.",[18],"Dietary Supplement: Dulcolax Suppositories",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Senna Tab","Senna 8.6mg two tablets per day post operative day 1 and and if needed, then continue on the same dose regiment until post operative day 5.",[9],[26],"Senokot",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Dulcolax Suppositories","Dulcolax 1 suppository to be placed rectally on the evening of post operative day 1 and if needed, then continue using the same dose regiment until the post operative day 5.",[15],[32],"Bisacodyl Suppositories",[34],{"name":35,"affiliation":5,"role":36},"Candace Parker-Autry, MD","PRINCIPAL_INVESTIGATOR",[38,44],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},"Christina M Mezes, MD","CONTACT","336-713-4098",null,"cmezes@wakehealth.edu",{"name":45,"role":40,"phone":41,"phoneExt":42,"email":46},"Sachin N Vyas, MS, PhD","svyas@wakehealth.edu",[48],{"facility":5,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"RECRUITING","Winston-Salem","North Carolina","27157","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-80.24422,36.09986,{"lat":59,"lon":58},[62,63],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},{"name":45,"role":40,"phone":64,"phoneExt":42,"email":46},"336.713.4098",{"type":66,"investigatorFullName":42,"investigatorTitle":42,"investigatorAffiliation":42,"oldNameTitle":42,"oldOrganization":42},"SPONSOR","100541894",false,"NCT06335797","Optimization of Postoperative Bowel Habits","Optimization of Postoperative Bowel Habits Following Pelvic Reconstructive Surgery: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Women ages 18 and older scheduled to undergo vaginal pelvic organ prolapse repair\n\nExclusion Criteria:\n\n* Women younger than 18 years old\n* Those unable to provide consent\n* Preexisting chronic laxative use\n* Conditions that could affect bowel function including, inflammatory bowel disease, irritable bowel syndrome, colorectal cancer, rectovaginal fistula; concurrent bowel surgery; intraoperative bowel injury","FEMALE","18 Years",{"count":76,"type":77},88,"ESTIMATED","INTERVENTIONAL",[80],"NA","Project is a trial, in which women undergoing vaginal surgery for pelvic organ prolapse will be randomized 1:1 to a postoperative bowel regimen of either oral senna or rectal bisacodyl suppository.",[83],"Constipation",[85,86,87],"Bowel Habits","Pelvic Surgery","Laxatives","2026-02-25",{"date":90,"type":91},"2026-02-27","ACTUAL",{"date":93,"type":91},"2024-10-16",{"date":95,"type":77},"2027-05",{"name":5,"class":6},1]