[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100524546":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":22,"centralContacts":26,"locations":36,"responsibleParty":86,"collaborators":21,"id":89,"slug":21,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":21,"eligibilityCriteria":94,"healthyVolunteers":95,"sex":96,"minAge":97,"maxAge":98,"enrollmentInfo":99,"targetDuration":21,"studyType":102,"phases":103,"briefSummary":105,"conditions":106,"keywords":21,"overallStatus":39,"whyStopped":21,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"University Hospital Bispebjerg and Frederiksberg","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"PrePROBE","Periodontal treament during pregnancy",[12],"Other: Periodontal treatment",{"label":14,"type":6,"description":15,"interventionNames":16},"PostPROBE","Peridontal treatment postpartum",[12],[18],{"type":6,"name":19,"description":19,"armGroupLabels":20,"otherNames":21},"Periodontal treatment",[14,9],null,[23],{"name":24,"affiliation":5,"role":25},"Berit Lilienthal Heitmann, Professor","PRINCIPAL_INVESTIGATOR",[27,32],{"name":28,"role":29,"phone":30,"phoneExt":21,"email":31},"Karoline Winckler, Phd","CONTACT","38163016","karoline.winckler@regionh.dk",{"name":33,"role":29,"phone":34,"phoneExt":21,"email":35},"Kathrine Bukkehave, Dentist","5155 9181","kathrine.hansen.bukkehave@regionh.dk",[37,59,68],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Holbaek Hospital","RECRUITING","Holbæk","Holbaek","4300","Denmark","DK",{"type":46,"coordinates":47},"Point",[48,49],11.71279,55.7175,{"lat":49,"lon":48},[52,56],{"name":53,"role":29,"phone":54,"phoneExt":21,"email":55},"Heidi Fischer, Midwife","59484320","hefi@regionsjaelland.dk",{"name":57,"role":29,"phone":54,"phoneExt":21,"email":58},"Signe Dueholm, Midwife","scdu@regionsjaelland.dk",{"facility":60,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},"Holbæk Hospital",{"type":46,"coordinates":62},[48,49],{"lat":49,"lon":48},[65,67],{"name":53,"role":29,"phone":66,"phoneExt":21,"email":55},"59 48 42 54",{"name":57,"role":29,"phone":54,"phoneExt":21,"email":58},{"facility":69,"status":39,"city":70,"state":70,"zip":71,"country":43,"countryCode":44,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"Nykøbing Falster Hospital","Nykøbing Falster","4800",{"type":46,"coordinates":73},[74,75],11.87425,54.76906,{"lat":75,"lon":74},[78,82],{"name":79,"role":29,"phone":80,"phoneExt":21,"email":81},"Pia Jensen, Secretary","56515412","pij@regionsjaelland.dk",{"name":83,"role":29,"phone":84,"phoneExt":21,"email":85},"Anette Jensen, Secretary","56515400","asj@regionsjaelland.dk",{"type":25,"investigatorFullName":87,"investigatorTitle":88,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Karoline Winckler","Phd, postdoc","100524546",false,"NCT06110143","Oral Health and Adverse Pregnancy Complications","The Prevention of Adverse Pregnancy Outcomes by Periodontal Treatment (PROBE) Intervention Study","Inclusion Criteria:\n\n* Pregnant women who are planned to give birth at either Holbaek or Nykoebing Falster hospital\n* Pregnant women diagnosed with periodontitis (stage I-III) by the study dentist\n\nExclusion Criteria:\n\n* Pregnant women without peridontitis\n* Pregnant women with less than 20 healthy teeths\n* Pregnant women with peridontitis and currently receiving treatment for peridontitis\n* Pregnant women with peridontitis stage IV",true,"FEMALE","16 Years","48 Years",{"count":100,"type":101},600,"ESTIMATED","INTERVENTIONAL",[104],"NA","Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected. Periodontitis is accompanied by a low-grade systemic inflammation and can be harmful to the general health of the woman, contribute to pre-term birth and adversely influence the future health and metabolism of the offspring. Despite this, studies indicate that 40% of Danish women in childbearing age do not visit a dentist regularly. The PROBE controlled intervention study will investigate the beneficial effect of treatment of periodontal disease during pregnancy on fetal growth, preterm delivery and birth weight.",[107,108,109,110,111,112],"Periodontal Diseases","Pregnancy Complications","Pregnancy Preterm","Gestational Diabetes","Preeclampsia","Inflammation","2025-03-25",{"date":115,"type":116},"2025-03-30","ACTUAL",{"date":118,"type":116},"2021-11-13",{"date":120,"type":101},"2026-05",{"name":5,"class":6},3]