PACT Involvement in Cardiology Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeUp to 18
SponsorThe Hospital for Sick Children

About this trial

The goal of this trial is to determine the effectiveness of a machine-learning (ML) model predicting a serious cardiac event within the next three months, when compared pre- versus post-deployment, in pediatric cardiac inpatients. The main questions it aims to answer are whether deployment of the ML model:

1. Increases PACT consultation within the next three months among admissions without PACT involvement in the previous 100 days 2. Increases PACT consultation or visit within the next three months among those who experience a serious cardiac event during this period 3. Decreases time to PACT consultation or visit among those seen by PACT during this period 4. Decreases the incidence of death in the intensive care unit (ICU) 5. Increases documentation of goals of care

High-risk cardiology patients will be identified by an ML model each morning. If the patient has been seen by the PACT team within the past year, the update will go to the PACT team members. If the patient hasn't been seen by the PACT team, the email will be sent to the cardiology physician in charge of the patient. This physician will decide whether a PACT consultation is necessary based on their clinical judgment. If so, a referral will be made using the usual process. Outcomes of the identified patients will be compared pre- and post-deployment.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Pediatric inpatients admitted to cardiology

Disqualifiers

Expected to be discharged prior to midnight on the day of admission

Trial design

Design model

Single group

Treatments tested in this trial

  • ML-based intervention

    Other intervention

    ML model predicting a serious cardiac event in cardiac patients, defined as VAD procedure, being wait listed for heart transplant or death within the next three months.

Treatment groups

1,000 Participants
are divided into 1 treatment group
Group A: ML modelExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Proportion of admissions with PACT consultation within the next three months among admissions without PACT involvement in the previous 100 days

The primary outcome will be the proportion of admissions with PACT consultation within the next three months among admissions without PACT involvement in the previous 100 days. This variable will be measured using SEDAR.

Time frame
Time of enrolment to 3 months

Secondary outcomes

1

PACT consultation or visit within the next three months among those with a positive model prediction

PACT consultation or visit within the next three months among those with a positive model prediction will be measured using SEDAR.

Time frame
Time of enrolment to 3 months
2

Time to PACT consultation or visit among those seen by PACT

Time to PACT consultation or visit among those seen by PACT will be measured using SEDAR.

Time frame
Time of enrolment to 3 months
3

Death in the ICU

Death in the ICU will be measured using SEDAR.

Time frame
Time of enrolment to 3 months
4

Documentation of goals of care

Goals of care will be abstracted via chart review.

Time frame
Time of enrolment to 3 months

Other outcomes

Sponsors and contacts

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