[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644936":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":10,"responsibleParty":21,"collaborators":10,"id":25,"slug":10,"hasResults":26,"nctId":27,"briefTitle":28,"officialTitle":29,"acronym":10,"eligibilityCriteria":30,"healthyVolunteers":31,"sex":32,"minAge":33,"maxAge":34,"enrollmentInfo":35,"targetDuration":10,"studyType":38,"phases":10,"briefSummary":39,"conditions":40,"keywords":10,"overallStatus":45,"whyStopped":10,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"FGR Group",null,"Singleton pregnancies diagnosed with fetal growth restriction (estimated fetal weight less than the 10th percentile for gestational age), undergoing Doppler assessment including aortic isthmus and other fetal vessels.",{"label":13,"type":10,"description":14,"interventionNames":10},"Control Group","Singleton pregnancies with normal fetal growth (estimated fetal weight above the 10th percentile), undergoing the same Doppler assessment as the FGR group for comparison.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Hanna Matt Louize, Specialist","CONTACT","+201287618565","hanna.matta0155@med.aun.edu.eg",{"type":22,"investigatorFullName":23,"investigatorTitle":24,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Hanna Matta louize","Obestetric and gynaecology specialist, Fetal and maternal ultrasound as subspecialty","100644936",false,"NCT07676708","Patterns of Aortic Isthmus Doppler in Early Fetal Growth Restriction , and the Changes in Aortic Isthmus Doppler Parameters With Every Changes of Other Early Iugr Parameters Like EFW, Uterine Artery Doppler, Cerebroplacental Ratio and Ductus Venosus Doppler in Comparison With Normal Group .","Patterns of Aortic Isthmus Doppler in Early Fetal Growth Restriction, Cross Sectional Comparative Study","Inclusion Criteria:\n\n* Singleton pregnancy\n* Diagnosis of fetal growth restriction (estimated fetal weight \\\u003C10th percentile for gestational age)\n* Written informed consent obtained from the patient\n\nExclusion Criteria:\n\n* Major fetal structural anomalies, especially cardiovascular anomalies\n* Multiple pregnancy (e.g., twins)\n* Suspected chromosomal abnormalities or genetic syndromes\n* Severe maternal comorbidities affecting Doppler results (e.g., uncontrolled diabetes, lupus)\n* Uncertain gestational age\n* Fetal demise before Doppler assessment",true,"FEMALE","18 Years","45 Years",{"count":36,"type":37},100,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the patterns of aortic isthmus Doppler in fetuses diagnosed with early fetal growth restriction (FGR) and to correlate these findings with the severity of FGR and other Doppler parameters.\n\nA cross-sectional comparative observational study will be conducted on singleton pregnant women attending the fetal medicine unit at Assiut University Hospital. Participants will be divided into two groups: fetuses with FGR and normal controls.\n\nDoppler measurements including aortic isthmus indices, uterine artery, umbilical artery, middle cerebral artery, cerebroplacental ratio, and ductus venosus will be assessed at a single time point. The study will help to clarify the clinical value of aortic isthmus Doppler in early detection and assessment of fetal compromise in FGR cases.",[41,42,43,44],"Fetal Growth Restriction","Placental Insufficiency","Aortic Isthmus Doppler","Cerebroplacental Ratio","NOT_YET_RECRUITING","2026-06-27",{"date":48,"type":49},"2026-06-30","ACTUAL",{"date":51,"type":37},"2026-07-01",{"date":53,"type":37},"2029-06-01",{"name":5,"class":6}]