PCA Administration in Prosthetic Joint Infection
ConditionProsthetic Joint Infection
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorDr. Dean Reeves Clinic
About this trial
Determine if dietary protocatechuic acid (PCA) will affect health biomarkers in patient undergoing revision surgery for a knee prosthetic joint infection
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
3 weeks or more after total knee arthroplasty
One or more symptoms of infection, including redness, swelling, pain, increasing range of motion loss, fever, nausea, and loss of appetite.
WBC count of aspirate >50,000 cells per μL
Disqualifiers
Not willing to undergo blood draw at 3 months.
Trial design
Design model
Single group
Treatments tested in this trial
Oral PCA
Dietary supplementPCA 1,000 mg BID until surgery, held until anticoagulation, and resumed at 1,000 mg daily for 4 years
Treatment groups
100 Participants
are divided into 1 treatment groupGroup A: PCA administratonOther 1 intervention
Trial outcomes
Primary outcomes
1
Change in immunity factor CXCL9 from 0 to 3 months
Time frame
0 and 3 months2
Change in HbA1c from 0 to 3 months
Time frame
0 and 3 monthsSecondary outcomes
1
Reinfection rate after revision for prosthetic joint infection
Time frame
0 to 4 yearsLocations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: