Health TrialsbyHealthPanel

Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Pilot Study

ConditionHIV/AIDS
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age15+
SponsorUniversity of California, San Francisco

About this trial

This study will refine and pilot test the Peer-led Dynamic Choice HIV Prevention (DCP) intervention in a single-arm pilot trial. The study will test the hypothesis that the Peer-led Dynamic Choice HIV Prevention intervention will be feasible and increase biomedical HIV prevention coverage in the 6 months after receipt of the Peer-led DCP intervention compared to the standard of care in the 6 months prior to intervention implementation.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age >=18 years or mature or mature minor >=15 years;

Female sex at birth;

HIV negative by country-standard testing algorithm

Elevated risk of HIV exposure, defined as at least 1 of the following: a) eligible for PrEP based on Uganda Ministry of Health Guidelines; b) exchange of sex for goods or money in last 6 months; or c) work in bar or guesthouse

Disqualifiers

Contraindication to country-recommended PrEP regimen per national guidelines

Participation in another HIV prevention study

Trial design

Design model

Single group

Treatments tested in this trial

  • Peer-led Dynamic Choice HIV Prevention (DCP) intervention

    Other intervention

    The intervention consists of peer mentor training on patient-centered choice counseling and Peer-led DCP services, and will be delivered by the peer mentor with clinician support: 1. HIV prevention product choice with option to switch over time 2. Rapid access to PEP from peer mentor for unplanned exposures 3. Integration of STI testing and treatment 4. Travel kit 5. Phone/SMS contact for peer support

Treatment groups

60 Participants
are divided into 1 treatment group
Group A: Peer-led Dynamic Choice HIV Prevention (DCP) interventionExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Biomedical HIV prevention coverage

Percentage of follow-up months that a participant uses a biomedical HIV prevention product

Time frame
24 weeks

Secondary outcomes

1

At-risk biomedical HIV prevention coverage

Percentage of at-risk follow-up months that a participant uses a biomedical HIV prevention product

Time frame
24 weeks
2

Feasibility of delivery of the Peer-Led DCP intervention by peers

Proportion of participants with Peer-led DCP intervention services delivered by peer mentor

Time frame
24 weeks

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of California, San Francisco

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator

Infectious Diseases Research Collaboration, Uganda

Collaborator

University of California, Berkeley

Collaborator

Source ClinicalTrials.gov
Apply now